SUMO1 抗体
Quick Overview for SUMO1 抗体 (ABIN4914409)
抗原
See all SUMO1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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免疫原
- Purified recombinant GST-SUMO1 fusion protein was used as immunogen.
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亚型
- IgG1
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anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) antibody
SUMO1 适用: 人, 大鼠, 小鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) antibodySUMO1 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-101) antibodySUMO1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D7 unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) antibodySUMO1 适用: 人, 大鼠 WB, IF, IHC, FACS, StM 宿主: 小鼠 Monoclonal SM1-495 unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (N-Term) antibodySUMO1 适用: 人, 大鼠, 小鼠 WB, IF, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-101) antibodySUMO1 适用: 人 WB, IF, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-30), (N-Term) antibodySUMO1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB0629 unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 55-86) antibodySUMO1 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 52-79) antibodySUMO1 适用: 人 WB, IF, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Small Ubiquitin Related Modifier Protein 1 (SUMO1) (AA 1-30) antibodySUMO1 适用: 人 WB, IF, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
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别名
- SUMO1
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背景
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Synonyms: DAP1, GMP1, PIC1, SMT3, UBL1, OFC10, SENP2, SMT3C, SMT3H3, Small ubiquitin-related modifier 1, SUMO-1, GAP-modifying protein 1, SMT3 homolog 3, Sentrin, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1, SUMO1, OK/SW-cl.43
Background: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalently attached to the voltage-gated potassium channel KCNB1, this modulates the gating characteristics of KCNB1 (PubMed:19223394). Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development. Covalently attached to ZFHX3 (PubMed:24651376).
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基因ID
- 7341
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UniProt
- P63165
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途径
- M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
抗原
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