FZR1 抗体
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北京 101111
Quick Overview for FZR1 抗体 (ABIN4909759)
抗原
See all FZR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Purified by Protein G.
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免疫原
- This FZR antibody is generated from a mouse immunized with a recombinant protein between1-496 amino acids from human FZR.
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亚型
- IgG1
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anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 1-493) antibody
FZR1 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 4C4 unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (N-Term) antibodyFZR1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 141-240) antibodyFZR1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 1-494) antibodyFZR1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4C4 unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 1-101) antibodyFZR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E12 unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 1-493) antibodyFZR1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 1-496) antibodyFZR1 适用: 人 WB 宿主: 小鼠 Monoclonal 1621CT637-76-67 unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (N-Term) antibodyFZR1 适用: 人, 小鼠, 大鼠, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (AA 35-84) antibodyFZR1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼, Pig, Bat, 猴, 小鸡, Hamster, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Fizzy/cell Division Cycle 20 Related 1 (FZR1) (N-Term) antibodyFZR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IF() -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- FZR1 (Fizzy/cell Division Cycle 20 Related 1 (FZR1))
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别名
- FZR
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背景
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Synonyms: FZR, CDH1, FZR2, HCDH, HCDH1, CDC20C, Fizzy-related protein homolog, CDC20-like protein 1, Cdh1/Hct1 homolog, FZR1, FYR, KIAA1242
Background: Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage checkpoint: its dephosphorylation and reassociation with the APC/C leads to the ubiquitination of PLK1, preventing entry into mitosis.
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基因ID
- 51343
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UniProt
- Q9UM11
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途径
- DNA Replication, Synthesis of DNA
抗原
-
