电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

ATG4C 抗体

This anti-ATG4C antibody is a 小鼠 单克隆 antibody detecting ATG4C in WB. Suitable for 小鼠.
产品编号 ABIN4906365
发货至: 中国

Quick Overview for ATG4C 抗体 (ABIN4906365)

抗原

See all ATG4C 抗体
ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

适用

  • 54
  • 35
  • 2
  • 2
  • 2
  • 1
  • 1
小鼠

宿主

  • 48
  • 9
  • 2
  • 1
小鼠

克隆类型

  • 50
  • 10
单克隆

标记

  • 31
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ATG4C antibody is un-conjugated

应用范围

  • 47
  • 24
  • 15
  • 13
  • 13
  • 10
  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)

克隆位点

7C2
  • 交叉反应

    小鼠

    纯化方法

    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This ATG4C monoclonal antibody is generated from mouse immunized with ATG4C recombinant protein.

    亚型

    IgG1
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

    别名

    ATG4C

    背景

    Synonyms: APG4C, AUTL1, AUTL3, APG4-C, Cysteine protease ATG4C, AUT-like 3 cysteine endopeptidase, Autophagin-3, Autophagy-related cysteine endopeptidase 3, Autophagy-related protein 4 homolog C, ATG4C

    Background: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

    基因ID

    84938

    UniProt

    Q96DT6

    途径

    Autophagy
You are here:
Chat with us!