ATG3 抗体
Quick Overview for ATG3 抗体 (ABIN4906359)
抗原
See all ATG3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by Protein G.
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免疫原
- This ATG3 antibody is generated from a mouse immunized with recombinant protein of human ATG3.
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亚型
- IgG1
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anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-100) antibody
ATG3 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2C10A12 unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-100) antibodyATG3 适用: 人, 猴 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 7A1D1 unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-314) antibodyATG3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) antibodyATG3 适用: 人, 大鼠, 犬, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 3C6 unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) antibodyATG3 适用: 人, 大鼠, 犬, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 3G3 unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) (Middle Region) antibodyATG3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-100) antibodyATG3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) (AA 51-150) antibodyATG3 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) (N-Term) antibodyATG3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-100) antibodyATG3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- ATG3 (ATG3 Autophagy Related 3 (ATG3))
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别名
- ATG3
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背景
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Synonyms: APG3, APG3L, PC3-96, APG3-LIKE, Ubiquitin-like-conjugating enzyme ATG3, Autophagy-related protein 3, hApg3, Protein PC3-96, ATG3
Background: E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8-like proteins. The formation of the ATG8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
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基因ID
- 64422
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UniProt
- Q9NT62
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途径
- Autophagy
抗原
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