E2F1 抗体 (acLys125)
Our Local Distributor
北京 101111
Quick Overview for E2F1 抗体 (acLys125) (ABIN4901417)
抗原
See all E2F1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- acLys125
-
原理
- E2F-1 is a protein encoded by the E2F1 gene which is approximately 46,9 kDa. E2F-1 is localised to the nucleus. It is involved in glioma, cyclins and cell cycle regulation and activation of BH3-only proteins. It plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. E2F-1 is expressed in the skin, pancreas and the nervous system. Mutations in the E2F1 gene may result in retinoblastoma pharyngoconjunctival fever. STJ98840 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous levels of E2F-1 (Acetyl-K125).
-
特异性
- This antibody detects endogenous levels of Histone H3 (Di-Methyl-K80). It doesn't reacte with total or Tri-Methy or Mono-Methyl protein.
-
产品特性
- Rabbit Polyclonal to Histone H3 (Di-Methyl-K80).
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized Tri-Methyl peptide derived from Human Histone H3
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:500-2000
ELISA 1:5000-20010 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
-
-
- E2F1 (E2F Transcription Factor 1 (E2F1))
-
别名
- E2F-1
-
基因ID
- 8350
-
UniProt
- P68431
-
途径
- p53 Pathway, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
抗原
-