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E2F1 抗体 (acLys125)

The 兔 多克隆 anti-E2F1 antibody is suitable to detect E2F1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN4901417
发货至: 中国
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Quick Overview for E2F1 抗体 (acLys125) (ABIN4901417)

抗原

See all E2F1 抗体
E2F1 (E2F Transcription Factor 1 (E2F1))

适用

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人, 小鼠, 大鼠

宿主

  • 224
  • 12
  • 2

克隆类型

  • 193
  • 45
多克隆

标记

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This E2F1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    acLys125

    原理

    E2F-1 is a protein encoded by the E2F1 gene which is approximately 46,9 kDa. E2F-1 is localised to the nucleus. It is involved in glioma, cyclins and cell cycle regulation and activation of BH3-only proteins. It plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. E2F-1 is expressed in the skin, pancreas and the nervous system. Mutations in the E2F1 gene may result in retinoblastoma pharyngoconjunctival fever. STJ98840 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous levels of E2F-1 (Acetyl-K125).

    特异性

    This antibody detects endogenous levels of Histone H3 (Di-Methyl-K80). It doesn't reacte with total or Tri-Methy or Mono-Methyl protein.

    产品特性

    Rabbit Polyclonal to Histone H3 (Di-Methyl-K80).

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized Tri-Methyl peptide derived from Human Histone H3

    亚型

    IgG
  • 应用备注

    WB 1:500-2000
    ELISA 1:5000-20010

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原

    E2F1 (E2F Transcription Factor 1 (E2F1))

    别名

    E2F-1

    基因ID

    8350

    UniProt

    P68431

    途径

    p53 Pathway, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
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