Beclin 1 抗体 (AA 110-190)
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北京 101111
Quick Overview for Beclin 1 抗体 (AA 110-190) (ABIN4901059)
抗原
See all Beclin 1 (BECN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 110-190
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原理
- Beclin-1 is a protein encoded by the ECN1 gene which is approximately 51,9 kDa. Beclin-1 is localised to the cytoplasm, Golgi apparatus and mitochondrion membrane. It is involved in the autophagy pathway, deubiquitination, metabolism of proteins, apelin signalling pathway and nanomaterial induced apoptosis. The beclin-1 protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which plays a role in multiple membrane trafficking pathways. PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. It also plays a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Beclin-1 is ubiquitously expressed. Mutations in the ECN1 gene can result in cervical cancer, breast cancer and Wolfram syndrome. STJ97761 was affinity-purified from rabbit. This antibody detects endogenous beclin-1.
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特异性
- Beclin-1 Mouse Monoclonal Antibody (5C2) detects endogenous levels of BECN1
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产品特性
- Mouse Monoclonal to Beclin-1.
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纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
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免疫原
- synthetic peptide derived from Beclin-1
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亚型
- IgG1
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anti-Beclin 1, Autophagy Related (BECN1) (AA 201-330) antibody
BECN1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 猴 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人, 大鼠, 猴, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) antibodyBECN1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2A4 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 1-354) antibodyBECN1 适用: 人, 小鼠, 大鼠 WB, IF, ICC, FACS, IP 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 210-239) antibodyBECN1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB7463 unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 210-239) antibodyBECN1 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 1-354) antibodyBECN1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Beclin 1, Autophagy Related (BECN1) (AA 1-273) antibodyBECN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:1000-2000
IHC 1:100-200 -
说明
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Ubiquitous.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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