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MYD88 抗体 (Internal Region)

MYD88 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4889359
发货至: 中国
  • 抗原 See all MYD88 抗体
    MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
    抗原表位
    • 15
    • 8
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 94
    • 62
    • 49
    • 16
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 猴
    宿主
    • 89
    • 10
    • 2
    克隆类型
    • 83
    • 18
    多克隆
    标记
    • 61
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYD88 antibody is un-conjugated
    应用范围
    • 82
    • 30
    • 22
    • 16
    • 14
    • 13
    • 13
    • 13
    • 9
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Reacts with Myd88 from human, mouse, rat, monkeys and other species (due to 100 % sequence homology)
    纯化方法
    Purified (protein A)
    免疫原
    Synthetic peptide of derived from internal part of human Myd88
    Top Product
    Discover our top product MYD88 Primary Antibody
  • 应用备注

    Working dilution: Optimal dilutions should be determined by the end user.
    The following are guidelines only:
    - WB : 1/500 to 1/2000 - ICC, IF: 1/200 to 1/1000

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Must be reconstituted in distilled water.
    浓度
    1 mg/mL
    缓冲液
    Tris 0,1M, glycine 0,1M
    储存条件
    4 °C/-20 °C
    储存方法
    Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
    有效期
    6 months
  • 抗原
    MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
    别名
    MyD88 (MYD88 产品)
    别名
    MYD88D antibody, XMyD88 antibody, myd88d antibody, MGC84928 antibody, CG2078 antibody, DMMYD88 antibody, DmMyD88 antibody, DmMyd88 antibody, Dmel\\CG2078 antibody, EP(2)2535 antibody, Kra antibody, LD20892 antibody, MYD88 antibody, MyD88 antibody, Myd88F antibody, dMyD88 antibody, dMyd88 antibody, kra antibody, myd88 antibody, zgc:103541 antibody, GB12344 antibody, NV10640 antibody, myd88-a antibody, myd88-b antibody, myeloid differentiation primary response 88 antibody, myeloid differentiation primary response 88 S homeolog antibody, myeloid differentiation primary response gene 88 antibody, CG2078 gene product from transcript CG2078-RB antibody, myeloid differentiation primary response protein MyD88-A antibody, myeloid differentiation primary response protein MyD88 antibody, myeloid differentiation factor 88 antibody, myeloid differentiation primary response 88 L homeolog antibody, MYD88 antibody, myd88.S antibody, Myd88 antibody, myd88 antibody, LOC413194 antibody, LOC100118553 antibody, LOC575153 antibody, myd88.L antibody
    背景
    Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.
    基因ID
    4615
    UniProt
    Q99836
    途径
    NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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