MYD88 抗体 (Internal Region)
Quick Overview for MYD88 抗体 (Internal Region) (ABIN4889359)
抗原
See all MYD88 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
特异性
- Reacts with Myd88 from human, mouse, rat, monkeys and other species (due to 100 % sequence homology)
-
纯化方法
- Purified (protein A)
-
免疫原
- Synthetic peptide of derived from internal part of human Myd88
-
-
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 201-296) antibody
MYD88 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IP, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 32-265) antibodyMYD88 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (Internal Region) antibodyVerified MYD88 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 44-264) antibodyMYD88 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) antibodyMYD88 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 136-164) antibodyMYD88 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) antibodyMYD88 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) antibodyMYD88 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 60-309) antibodyMYD88 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 60-309) antibodyMYD88 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000 - ICC, IF: 1/200 to 1/1000 -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Must be reconstituted in distilled water.
-
浓度
- 1 mg/mL
-
缓冲液
- Tris 0,1M, glycine 0,1M
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
-
有效期
- 6 months
-
-
- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
-
别名
- MyD88
-
背景
- Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.
-
基因ID
- 4615
-
UniProt
- Q99836
-
途径
- NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
抗原
-
