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SYN1 抗体 (C-Term)

This anti-SYN1 antibody is a 兔 多克隆 antibody detecting SYN1 in WB 和 IHC. Suitable for 人, 大鼠 和 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN4886734
发货至: 中国

Quick Overview for SYN1 抗体 (C-Term) (ABIN4886734)

抗原

See all SYN1 抗体
SYN1 (Synapsin I (SYN1))

适用

  • 112
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  • 1
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人, 大鼠, 小鼠

宿主

  • 126
  • 8

克隆类型

  • 117
  • 17
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
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This SYN1 antibody is un-conjugated

应用范围

  • 98
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 28
    • 15
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 662-705, C-Term

    原理

    Anti-Synapsin I/SYN1 Antibody Picoband®

    序列

    KSQSLTNAFN LPEPAPPRPS LSQDEVKAET IRSLRKSFAS L

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Synapsin I/SYN1 Antibody Picoband® (ABIN4886734). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Synapsin I, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. "Entrez Gene: SYN1 synapsin I". 2. Huttner WB, Schiebler W, Greengard P, De Camilli P (May 1983). "Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation". J. Cell Biol. 96 (5): 1374-88. 3. Südhof TC (May 1990). "The structure of the human synapsin I gene and protein". J. Biol. Chem. 265 (14): 7849-52.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Tian, Lin, Wu, Li, Liu, Yan, Liu, Xi: "Neurotoxicity induced by zinc oxide nanoparticles: age-related differences and interaction." in: Scientific reports, Vol. 5, pp. 16117, (2016) (PubMed).

    Huang, Zhu, Zhang, Zhu, Liu, Zhu, Wang, Li, Yang, Dong, Liu, Chen, Zhang, Yang, Deng, Fan, Wang, Liu, Ma, Fu, Wu: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).

  • 抗原

    SYN1 (Synapsin I (SYN1))

    别名

    SYN1

    背景

    Synonyms: Synapsin-1,Brain protein 4.1,Synapsin I,SYN1,

    Tissue Specificity: Ubiquitous. Expressed in leukocytes and plasma. .

    Background: Synapsin I, is the collective name for Synapsin Ia and Synapsin Ib, two nearly identical phosphoproteins that in humans are encoded by the SYN1 gene. This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

    分子量

    78 kDa

    基因ID

    6853

    UniProt

    P17600
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