SLC1A3 抗体 (N-Term)
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Quick Overview for SLC1A3 抗体 (N-Term) (ABIN4886724)
抗原
See all SLC1A3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-42, N-Term
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原理
- Anti-EAAT1/SLC1A3 Antibody
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序列
- RMERFQQGVR KRTLLAKKKV QNITKEDVK
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-EAAT1/SLC1A3 Antibody (ABIN4886724). Tested in WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human EAAT1, different from the related mouse sequence by three amino acids, and identical to the related rat sequence.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Tumor necrosis factor-? promotes the expression of excitatory amino-acid transporter 2 in astrocytes: Optimal concentration and incubation time." in: Experimental and therapeutic medicine, Vol. 8, Issue 6, pp. 1909-1913, (2014) (PubMed).
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: "Tumor necrosis factor-? promotes the expression of excitatory amino-acid transporter 2 in astrocytes: Optimal concentration and incubation time." in: Experimental and therapeutic medicine, Vol. 8, Issue 6, pp. 1909-1913, (2014) (PubMed).
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- SLC1A3 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3))
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别名
- SLC1A3
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背景
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Synonyms: Excitatory amino acid transporter 1,Sodium-dependent glutamate/aspartate transporter 1,GLAST-1,Solute carrier family 1 member 3,SLC1A3,EAAT1, GLAST, GLAST1,
Tissue Specificity: Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia.
Background: Solute carrier family 1 (glial high-affinity glutamate transporter), member 3, also known as SLC1A3, EAAT1 or GLAST, is a protein that in humans is encoded by the SLC1A3 gene. This gene is a member of high affinity glutamate transporter family. It is mapped to chromosome 5p13.2 by fluorescence in situ hybridization (FISH). And this gene transports L-glutamate and also L- and D-aspartate. It is essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Furthermore, this gene acts as a symport by cotransporting sodium.
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分子量
- 60 kDa
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基因ID
- 6507
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UniProt
- P43003
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途径
- Sensory Perception of Sound, Synaptic Membrane, Dicarboxylic Acid Transport
抗原
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