SLC1A3 抗体 (C-Term)
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北京 101111
Quick Overview for SLC1A3 抗体 (C-Term) (ABIN3044001)
抗原
See all SLC1A3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 519-537, C-Term
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原理
- Anti-EAAT1/SLC1A3 Antibody
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序列
- MKKPYQLIAQ DNETEKPID
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-EAAT1/SLC1A3 Antibody (ABIN3044001). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human EAAT1, different from the related rat and mouse sequences by three amino acids.
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亚型
- IgG
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anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (AA 522-541) antibody
KO Validated SLC1A3 适用: 人, 大鼠, 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) antibodySLC1A3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (AA 301-400) antibodySLC1A3 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (AA 14-42), (N-Term) antibodySLC1A3 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (AA 146-236) antibodySLC1A3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (AA 188-200), (Extracellular) antibodySLC1A3 适用: 大鼠 WB, IHC, FACS, IF, LCI, IC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (Cytoplasmic Domain) antibodySLC1A3 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (Cytoplasmic Domain) antibodySLC1A3 适用: 人, 大鼠, 小鼠, 猴, 兔, Hamster, Cow, 马, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (AA 1-542) antibodySLC1A3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) (AA 162-237) antibodySLC1A3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D1 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μ/mL, Human, Mouse, Rat
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Rat, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes." in: Stem cell reports, Vol. 9, Issue 2, pp. 615-628, (2018) (PubMed).
: "Tumor necrosis factor-? promotes the expression of excitatory amino-acid transporter 2 in astrocytes: Optimal concentration and incubation time." in: Experimental and therapeutic medicine, Vol. 8, Issue 6, pp. 1909-1913, (2014) (PubMed).
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: "Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes." in: Stem cell reports, Vol. 9, Issue 2, pp. 615-628, (2018) (PubMed).
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- SLC1A3 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3))
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别名
- SLC1A3
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背景
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Synonyms: Excitatory amino acid transporter 1,Sodium-dependent glutamate/aspartate transporter 1,GLAST-1,Solute carrier family 1 member 3,SLC1A3,EAAT1, GLAST, GLAST1,
Tissue Specificity: Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia.
Background: Solute carrier family 1 (glial high-affinity glutamate transporter), member 3, also known as SLC1A3, EAAT1 or GLAST, is a protein that in humans is encoded by the SLC1A3 gene. This gene is a member of high affinity glutamate transporter family. SLC1A3 is mapped to chromosome 5p13.2 by fluorescence in situ hybridization (FISH). This gene transports L-glutamate and also L- and D-aspartate. It is essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. This gene acts as a symport by cotransporting sodium.
Sequence Similarities: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
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分子量
- 274 kDa
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UniProt
- P43003
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途径
- Sensory Perception of Sound, Synaptic Membrane, Dicarboxylic Acid Transport
抗原
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