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GADD45A 抗体 (C-Term)

GADD45A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4886599
发货至: 中国
  • 抗原 See all GADD45A 抗体
    GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
    抗原表位
    • 16
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    AA 125-165, C-Term
    适用
    • 45
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    宿主
    • 39
    • 8
    克隆类型
    • 41
    • 6
    多克隆
    标记
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    This GADD45A antibody is un-conjugated
    应用范围
    • 40
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    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Growth arrest and DNA damage-inducible protein GADD45 alpha(GADD45A) detection. Tested with WB in Human.
    序列
    VLVTNPHSSQ WKDPALSQLI CFCRESRYMD QWVPVINLP
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Growth arrest and DNA damage-inducible protein GADD45 alpha(GADD45A) detection. Tested with WB in Human.
    Gene Name: growth arrest and DNA-damage-inducible, alpha
    Protein Name: Growth arrest and DNA damage-inducible protein GADD45 alpha
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human GADD45A (125-165aa VLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLP ER), identical to the related mouse and rat sequences.
    亚型
    IgG
    Top Product
    Discover our top product GADD45A Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
    别名
    GADD45A (GADD45A 产品)
    别名
    MGC53491 antibody, zgc:91795 antibody, gadd45a antibody, GADD45A antibody, ddit1 antibody, gadd45 antibody, GADD45 antibody, AA545191 antibody, Ddit1 antibody, DDIT1 antibody, Gadd45 antibody, growth arrest and DNA damage inducible alpha L homeolog antibody, growth arrest and DNA-damage-inducible, alpha, b antibody, growth arrest and DNA damage inducible alpha antibody, growth arrest and DNA damage-inducible protein 45 antibody, growth arrest and DNA-damage-inducible 45 alpha antibody, growth arrest and DNA-damage-inducible, alpha antibody, gadd45a.L antibody, gadd45ab antibody, GADD45A antibody, gadd45a antibody, GADD45 antibody, Gadd45a antibody
    背景
    Growth arrest and DNA-damage-inducible protein GADD45 alpha (GADD45A) is a protein that in humans is encoded by the GADD45A gene. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. It is located on 1p34-p12. Sequence analysis of human and hamster cDNA clones demonstrated that the gene has been highly conserved and encodes a novel 165-amino acid polypeptide. Northern blot analysis detected moderate expression of a 1.4-kb GADD45A transcript in heart, skeletal muscle, and kidney, with little or no expression in brain, placenta, lung, liver, and pancreas. In addition, Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

    Synonyms: DDIT1 | DDIT-1 | DDIT1 | GADD45 | GA45A | GADD45A | P24522
    基因ID
    1647
    UniProt
    P24522
    途径
    p53 Pathway, Cell Division Cycle
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