GADD45A 抗体 (C-Term)
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北京 101111
Quick Overview for GADD45A 抗体 (C-Term) (ABIN4886599)
抗原
See all GADD45A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 125-165, C-Term
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原理
- Anti-GADD45A Antibody
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序列
- VLVTNPHSSQ WKDPALSQLI CFCRESRYMD QWVPVINLP
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-GADD45A Antibody (ABIN4886599). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human GADD45A, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) antibody
GADD45A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 65-165) antibodyGADD45A 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (N-Term) antibodyGADD45A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 76-165) antibodyGADD45A 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3D12 unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-30), (N-Term) antibodyGADD45A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB16520 unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 133-165), (C-Term) antibodyGADD45A 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB16521 unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) antibodyGADD45A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) antibodyGADD45A 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) antibodyGADD45A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 90-139) antibodyGADD45A 适用: 人, Cow WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
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别名
- GADD45A
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背景
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Synonyms: Growth arrest and DNA damage-inducible protein GADD45 alpha,DNA damage-inducible transcript 1 protein,DDIT-1,GADD45A,DDIT1, GADD45,
Tissue Specificity: Predominantly expressed in kidney and brain. Detected at much lower levels in heart and skeletal muscle. .
Background: Growth arrest and DNA-damage-inducible protein GADD45 alpha (GADD45A) is a protein that in humans is encoded by the GADD45A gene. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. It is located on 1p34-p12. Sequence analysis of human and hamster cDNA clones demonstrated that the gene has been highly conserved and encodes a novel 165-amino acid polypeptide. Northern blot analysis detected moderate expression of a 1.4-kb GADD45A transcript in heart, skeletal muscle, and kidney, with little or no expression in brain, placenta, lung, liver, and pancreas. In addition, Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.
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分子量
- 19 kDa
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基因ID
- 1647
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UniProt
- P24522
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途径
- p53 Pathway, Cell Division Cycle
抗原
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