GADD45A 抗体 (C-Term)
Quick Overview for GADD45A 抗体 (C-Term) (ABIN4886599)
抗原
See all GADD45A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 125-165, C-Term
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原理
- Anti-GADD45A Antibody Picoband®
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序列
- VLVTNPHSSQ WKDPALSQLI CFCRESRYMD QWVPVINLP
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-GADD45A Antibody Picoband® (ABIN4886599). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human GADD45A, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) antibody
GADD45A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 65-165) antibodyGADD45A 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 76-165) antibodyGADD45A 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3D12 unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (N-Term) antibodyGADD45A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 133-165), (C-Term) antibodyGADD45A 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB16521 unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-30), (N-Term) antibodyGADD45A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB16520 unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) antibodyGADD45A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) antibodyGADD45A 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) antibodyGADD45A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 90-139) antibodyGADD45A 适用: 人, Cow WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. Barreto, G., Schafer, A. Marhold, J., Stach, D., Swaminathan, S. K., Handa, V., Doderlein, G., Maltry, N., Wu, W., Lyko, F., Niehrs, C.Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.Nature445: 671-675, 2007. 2. Papathanasiou MA, Kerr NC, Robbins JH, McBride OW, Alamo I Jr, Barrett SF, Hickson ID, Fornace AJ Jr (Mar 1991). "Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C". Mol Cell Biol 11 (2): 1009-16. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
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别名
- GADD45A
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背景
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Synonyms: Growth arrest and DNA damage-inducible protein GADD45 alpha,DNA damage-inducible transcript 1 protein,DDIT-1,GADD45A,DDIT1, GADD45,
Tissue Specificity: Predominantly expressed in kidney and brain. Detected at much lower levels in heart and skeletal muscle. .
Background: Growth arrest and DNA-damage-inducible protein GADD45 alpha (GADD45A) is a protein that in humans is encoded by the GADD45A gene. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. It is located on 1p34-p12. Sequence analysis of human and hamster cDNA clones demonstrated that the gene has been highly conserved and encodes a novel 165-amino acid polypeptide. Northern blot analysis detected moderate expression of a 1.4-kb GADD45A transcript in heart, skeletal muscle, and kidney, with little or no expression in brain, placenta, lung, liver, and pancreas. In addition, Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.
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分子量
- 19 kDa
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基因ID
- 1647
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UniProt
- P24522
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途径
- p53 Pathway, Cell Division Cycle
抗原
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