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GADD45A 抗体 (C-Term)

This anti-GADD45A antibody is a 兔 多克隆 antibody detecting GADD45A in WB. Suitable for 人.
产品编号 ABIN4886599
发货至: 中国

Quick Overview for GADD45A 抗体 (C-Term) (ABIN4886599)

抗原

See all GADD45A 抗体
GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

适用

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宿主

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克隆类型

  • 45
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多克隆

标记

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This GADD45A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 125-165, C-Term

    原理

    Anti-GADD45A Antibody

    序列

    VLVTNPHSSQ WKDPALSQLI CFCRESRYMD QWVPVINLP

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-GADD45A Antibody (ABIN4886599). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human GADD45A, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))

    别名

    GADD45A

    背景

    Synonyms: Growth arrest and DNA damage-inducible protein GADD45 alpha,DNA damage-inducible transcript 1 protein,DDIT-1,GADD45A,DDIT1, GADD45,

    Tissue Specificity: Predominantly expressed in kidney and brain. Detected at much lower levels in heart and skeletal muscle. .

    Background: Growth arrest and DNA-damage-inducible protein GADD45 alpha (GADD45A) is a protein that in humans is encoded by the GADD45A gene. This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. It is located on 1p34-p12. Sequence analysis of human and hamster cDNA clones demonstrated that the gene has been highly conserved and encodes a novel 165-amino acid polypeptide. Northern blot analysis detected moderate expression of a 1.4-kb GADD45A transcript in heart, skeletal muscle, and kidney, with little or no expression in brain, placenta, lung, liver, and pancreas. In addition, Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

    分子量

    19 kDa

    基因ID

    1647

    UniProt

    P24522

    途径

    p53 Pathway, Cell Division Cycle
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