CXCL3 抗体 (AA 32-100)
Quick Overview for CXCL3 抗体 (AA 32-100) (ABIN4886553)
抗原
See all CXCL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 32-100
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原理
- Anti-GRO gamma/CXCL3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-GRO gamma/CXCL3 Antibody Picoband® (ABIN4886553). Tested in ELISA, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived mouse GRO gamma recombinant protein (Position: S32-S100). Mouse GRO gamma shares 60.6% and 90.6% amino acid (aa) sequence identity with human and rat GRO gamma, respectively.
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亚型
- IgG
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anti-Chemokine (C-X-C Motif) Ligand 3 (CXCL3) (AA 35-107) antibody
CXCL3 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 3 (CXCL3) (C-Term) antibodyCXCL3 适用: 人, 小鼠, 大鼠 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 3 (CXCL3) (AA 41-113) antibodyCXCL3 适用: 马 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 3 (CXCL3) (AA 35-107) antibodyCXCL3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 3 (CXCL3) (AA 35-107) antibodyCXCL3 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA, 0.1-0.5 μg/mL, -
Western blot, 0.1-0.5 μg/mL, Mouse
1. Ahuja SK, Murphy PM (August 1996). "The CXC chemokines growth-regulated oncogene (GRO) alpha, GRObeta, GROgamma, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor". J. Biol. Chem. 271 (34): 20545-50. 2. Farioli-Vecchioli S, Cinà I, Ceccarelli M, Micheli L, Leonardi L, Ciotti MT, De Bardi M, Di Rocco C, Pallini R, Cavallaro S, Tirone F (October 2012). "Tis21 knock-out enhances the frequency of medulloblastoma in patched1 heterozygous mice by inhibiting the cxcl3-dependent migration of cerebellar neurons". The Journal of neuroscience : the official journal of the Society for Neuroscience 32 (44): 15547-15564. 3. Smith DF, Galkina E, Ley K, Huo Y (November 2005). "GRO family chemokines are specialized for monocyte arrest from flow". Am. J. Physiol. Heart Circ. Physiol. 289 (5): H1976-84. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))
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别名
- CXCL3
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背景
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Synonyms: C-X-C motif chemokine 3,Dendritic cell inflammatory protein 1 ,Cxcl3 ,Dcip1 , Gm1960 ,
Tissue Specificity: Expressed in eye lens. .
Background: Chemokine (C-X-C motif) ligand 3 (CXCL3), also known as GRO protein gamma (GROg) and macrophage inflammatory protein-2-beta (MIP2b), is a small cytokine belonging to the CXC chemokine family. It is mapped to 14p2. CXCL3 controls migration and adhesion of monocytes and mediates its effects on its target cell by interacting with a cell surface chemokine receptor. It has been shown that CXCL3 regulates cell autonomously the migration of the precursors of cerebellar granule neurons toward the internal layers of cerebellum, during the morphogenesis of cerebellum. CXCL3 also play fundamental roles in the development, homeostasis and it has effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
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分子量
- 25 kDa
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基因ID
- 330122
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UniProt
- Q6W5C0
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途径
- Cellular Response to Molecule of Bacterial Origin, Autophagy
抗原
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