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AMACR 抗体 (Middle Region)

AMACR 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4886454
发货至: 中国
  • 抗原 See all AMACR 抗体
    AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
    抗原表位
    • 19
    • 14
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 208-246, Middle Region
    适用
    • 110
    • 31
    • 29
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 77
    • 35
    • 2
    克隆类型
    • 64
    • 50
    多克隆
    标记
    • 63
    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AMACR antibody is un-conjugated
    应用范围
    • 87
    • 53
    • 44
    • 35
    • 17
    • 17
    • 14
    • 13
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Alpha-methylacyl-CoA racemase(AMACR) detection. Tested with WB in Human,Rat.
    序列
    RGQNMLDGGA PFYTTYRTAD GEFMAVGAIE PQFYELLIK
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Alpha-methylacyl-CoA racemase(AMACR) detection. Tested with WB in Human,Rat.
    Gene Name: alpha-methylacyl-CoA racemase
    Protein Name: Alpha-methylacyl-CoA racemase
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human AMACR (208-246aa RGQNMLDGGAPFYTTYRTADGEFMAVGAIEPQFYELLIK), different from the related mouse and rat sequences by four amino acids.
    亚型
    IgG
    Top Product
    Discover our top product AMACR Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Wang, Tian, Xiao, Zhang, Sun, Tang: "A metanephric adenoma of the kidney associated with polycythemia: A case report." in: Oncology letters, Vol. 11, Issue 1, pp. 352-354, (2016) (PubMed).

  • 抗原
    AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
    别名
    AMACR (AMACR 产品)
    别名
    AMACR antibody, DKFZp469O1232 antibody, amacr antibody, NCU04099.1 antibody, MGC89832 antibody, AMACRD antibody, CBAS4 antibody, RACE antibody, RM antibody, Macr1 antibody, Da1-8 antibody, Marc1 antibody, alpha-methylacyl-CoA racemase antibody, PROBABLE ALPHA-METHYLACYL-COA RACEMASE MCR (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase) antibody, Alpha-methylacyl-CoA racemase antibody, alpha-methylacyl-CoA racemase L homeolog antibody, AMACR antibody, mcr antibody, BPSL0064 antibody, Maqu_2037 antibody, UREG_03852 antibody, MCYG_01809 antibody, amacr antibody, amacr.L antibody, MGYG_04259 antibody, NCU04099 antibody, Amacr antibody
    背景
    Alpha-methylacyl-CoA racemase (AMACR) is a mitochondrial and peroxisomal enzyme. It encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

    Synonyms: 2 arylpropionyl CoA epimerase | 2 methylacyl CoA racemase | 2-methylacyl-CoA racemase | Alpha methylacyl CoA racemase | Alpha-methylacyl-CoA racemase | Amacr | CBAS4 | Da1-8 | Macr1 | RACE | RM | Q9UHK6
    基因ID
    23600
    途径
    Monocarboxylic Acid Catabolic Process
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