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ALDH1A2 抗体 (AA 1-110)

This anti-ALDH1A2 antibody is a 兔 多克隆 antibody detecting ALDH1A2 in WB, IHC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4886449
发货至: 中国

Quick Overview for ALDH1A2 抗体 (AA 1-110) (ABIN4886449)

抗原

See all ALDH1A2 抗体
ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ALDH1A2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
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    AA 1-110

    原理

    Anti-ALDH1A2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-ALDH1A2 Antibody Picoband® (ABIN4886449). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ALDH1A2 recombinant protein (Position: M1-A110). Human ALDH1A2 shares 95.5% amino acid (aa) sequence identity with both mouse and rat ALDH1A2.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. "Entrez Gene: ALDH1A2 aldehyde dehydrogenase 1 family, member A2". 2. Ono Y, Fukuhara N, Yoshie O (Dec 1998). "TAL1 and LIM-Only Proteins Synergistically Induce Retinaldehyde Dehydrogenase 2 Expression in T-Cell Acute Lymphoblastic Leukemia by Acting as Cofactors for GATA3". Mol Cell Biol 18 (12): 6939-50.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

    别名

    ALDH1A2

    背景

    Synonyms: Retinal dehydrogenase 2,RALDH 2,RalDH2,1.2.1.36,Aldehyde dehydrogenase family 1 member A2,Retinaldehyde-specific dehydrogenase type 2,RALDH (II),ALDH1A2,RALDH2,

    Tissue Specificity: Widely expressed. Expressed at higher level in thymus (medullary epithelial cells and monocyte-dendritic cells), pancreas, adrenal cortex and testis. Expressed at lower level in the spleen, fetal liver and lymph nodes. Isoform 2 and isoform 3 seem to be less frequently expressed than isoform 1, if at all.

    Background: Aldehyde dehydrogenase 1 family, member A2, also known as ALDH1A2 or retinaldehyde dehydrogenase 2 (RALDH2), is an enzyme that in humans is encoded by the ALDH1A2 gene. This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

    分子量

    57 kDa

    基因ID

    8854

    UniProt

    O94788

    途径

    Retinoic Acid Receptor Signaling Pathway
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