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EPH Receptor A2 抗体

EPHA2 适用: 人 FACS, IF, EIA 宿主: 小鼠 Monoclonal GM5H5 unconjugated
产品编号 ABIN488132
发货至: 中国
  • 抗原 See all EPH Receptor A2 (EPHA2) 抗体
    EPH Receptor A2 (EPHA2)
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This EPH Receptor A2 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    Recognizes EphA2 receptor tyrosine kinase (EphA2).
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography on Protein G.
    免疫原
    Genetic immunisation with cDNA encoding Human EphA2 Remarks: Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
    克隆位点
    GM5H5
    亚型
    IgG1
    Top Product
    Discover our top product EPHA2 Primary Antibody
  • 应用备注
    cELISA: 1/200-1/400. Flow Cytometry: 1.2 μg/10^6 cells. Immunofluorescence: 1 μg/10^6 cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    2.0 mg/mL
    缓冲液
    Phosphate buffered saline, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    EPH Receptor A2 (EPHA2)
    别名
    EPHA2 / ECK (EPHA2 产品)
    别名
    ARCC2 antibody, CTPA antibody, CTPP1 antibody, CTRCT6 antibody, ECK antibody, epha2 antibody, MGC89505 antibody, AW545284 antibody, Eck antibody, Myk2 antibody, Sek-2 antibody, Sek2 antibody, id:ibd5152 antibody, rtk6 antibody, G42 antibody, XE10 antibody, epha2-A antibody, EPH receptor A2 antibody, Eph receptor A2 antibody, epoxide hydrolase antibody, eph receptor A2 a antibody, EPH receptor A2 L homeolog antibody, EPHA2 antibody, Epha2 antibody, epha2 antibody, ephA2 antibody, epha2a antibody, epha2.L antibody
    背景
    EphA2 (Eph receptor tyrosine kinase A2) belongs to the Eph tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130 kDA transmembrane protein which is primarily found in adult human epithelial cells (1). Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis (2,3). The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, EphA2 is overexpressed in prostate, lung and colon cancers and 40 % of breast cancers and it represent an attractive potential target for drug design (3,4).Synonyms: Eph receptor A2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK
    基因ID
    1969
    NCBI登录号
    NP_004422
    UniProt
    P29317
    途径
    RTK signaling
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