EPH Receptor A2 抗体
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- 抗原 See all EPH Receptor A2 (EPHA2) 抗体
- EPH Receptor A2 (EPHA2)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This EPH Receptor A2 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- Recognizes EphA2 receptor tyrosine kinase (EphA2).
- 交叉反应 (详细)
- Species reactivity (tested):Human.
- 纯化方法
- Affinity Chromatography on Protein G.
- 免疫原
- Genetic immunisation with cDNA encoding Human EphA2 Remarks: Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
- 克隆位点
- GM5H5
- 亚型
- IgG1
- Top Product
- Discover our top product EPHA2 Primary Antibody
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- 应用备注
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cELISA: 1/200-1/400. Flow Cytometry: 1.2 μg/10^6 cells. Immunofluorescence: 1 μg/10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 2.0 mg/mL
- 缓冲液
- Phosphate buffered saline, pH 7.2
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- EPH Receptor A2 (EPHA2)
- 别名
- EPHA2 / ECK (EPHA2 产品)
- 背景
- EphA2 (Eph receptor tyrosine kinase A2) belongs to the Eph tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130 kDA transmembrane protein which is primarily found in adult human epithelial cells (1). Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis (2,3). The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, EphA2 is overexpressed in prostate, lung and colon cancers and 40 % of breast cancers and it represent an attractive potential target for drug design (3,4).Synonyms: Eph receptor A2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK
- 基因ID
- 1969
- NCBI登录号
- NP_004422
- UniProt
- P29317
- 途径
- RTK signaling
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