EPH Receptor A2 抗体
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北京 101111
Quick Overview for EPH Receptor A2 抗体 (ABIN488132)
抗原
See all EPH Receptor A2 (EPHA2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes EphA2 receptor tyrosine kinase (EphA2).
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography on Protein G.
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免疫原
- Genetic immunisation with cDNA encoding Human EphA2 Remarks: Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
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亚型
- IgG1
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anti-EPH Receptor A2 (EPHA2) (AA 30-60), (N-Term) antibody
EPHA2 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB01579 unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 901-976) antibodyEPHA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 204-326) antibodyEPHA2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-EPH Receptor A2 (EPHA2) antibodyEPHA2 适用: 人 FACS, IF, cELISA 宿主: 小鼠 Monoclonal Kalpha-5H5 unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 30-60) antibodyEPHA2 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 333-347), (Extracellular) antibodyEPHA2 适用: 人 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 847-976) antibodyEPHA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (Tyr588), (Tyr596) antibodyEPHA2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2 (EPHA2) (AA 559-976) antibodyEPHA2 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3D7 unconjugated
anti-EPH Receptor A2 (EPHA2) antibodyEPHA2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1B3C7 unconjugated
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应用备注
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cELISA: 1/200-1/400. Flow Cytometry: 1.2 μg/10^6 cells. Immunofluorescence: 1 μg/10^6 cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 2.0 mg/mL
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缓冲液
- Phosphate buffered saline, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- EPH Receptor A2 (EPHA2)
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别名
- EPHA2 / ECK
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背景
- EphA2 (Eph receptor tyrosine kinase A2) belongs to the Eph tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130 kDA transmembrane protein which is primarily found in adult human epithelial cells (1). Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis (2,3). The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, EphA2 is overexpressed in prostate, lung and colon cancers and 40 % of breast cancers and it represent an attractive potential target for drug design (3,4).Synonyms: Eph receptor A2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK
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基因ID
- 1969
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NCBI登录号
- NP_004422
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UniProt
- P29317
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途径
- RTK signaling
抗原
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