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EPH Receptor A2 抗体

EPHA2 适用: 人 FACS, IF, EIA 宿主: 小鼠 Monoclonal GM5H5 unconjugated
产品编号 ABIN488132
发货至: 中国
  • 抗原 See all EPH Receptor A2 (EPHA2) 抗体
    EPH Receptor A2 (EPHA2)
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This EPH Receptor A2 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    Recognizes EphA2 receptor tyrosine kinase (EphA2).
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography on Protein G.
    免疫原
    Genetic immunisation with cDNA encoding Human EphA2 Remarks: Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
    克隆位点
    GM5H5
    亚型
    IgG1
    Top Product
    Discover our top product EPHA2 Primary Antibody
  • 应用备注
    cELISA: 1/200-1/400. Flow Cytometry: 1.2 μg/10^6 cells. Immunofluorescence: 1 μg/10^6 cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    2.0 mg/mL
    缓冲液
    Phosphate buffered saline, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    EPH Receptor A2 (EPHA2)
    别名
    EPHA2 / ECK (EPHA2 产品)
    背景
    EphA2 (Eph receptor tyrosine kinase A2) belongs to the Eph tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130 kDA transmembrane protein which is primarily found in adult human epithelial cells (1). Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis (2,3). The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, EphA2 is overexpressed in prostate, lung and colon cancers and 40 % of breast cancers and it represent an attractive potential target for drug design (3,4).Synonyms: Eph receptor A2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK
    基因ID
    1969
    NCBI登录号
    NP_004422
    UniProt
    P29317
    途径
    RTK signaling
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