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CDK6 抗体

This anti-CDK6 antibody is a 小鼠 单克隆 antibody detecting CDK6 in WB 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN488121
发货至: 中国

Quick Overview for CDK6 抗体 (ABIN488121)

抗原

See all CDK6 抗体
CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

适用

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  • 45
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  • 6
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  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 104
  • 17
小鼠

克隆类型

  • 90
  • 31
单克隆

标记

  • 68
  • 6
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This CDK6 antibody is un-conjugated

应用范围

  • 73
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  • 27
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  • 17
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  • 8
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  • 2
  • 2
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  • 1
Western Blotting (WB), Immunoprecipitation (IP)

克隆位点

DCS-83
  • 特异性

    This antibody reacts with Cdk6.

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse and Rat.

    纯化方法

    Protein-A Sepharose Chromatography.

    免疫原

    Recombinant Cdk6 protein. Remarks: Hybridoma was established by fusion of mouse myeloma cell NS-2 with Balb/c mouse splenocyte.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.2 containing 50 % Glycerol without preservatives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原

    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

    别名

    CDK6

    背景

    Cdk6 (Cyclin-dependent kinase-6) is a 38-40 kDa member of the Cdk family of mitotic kinases involved in cell cycle progression. The Cdk6 phosphoprotein, like Cdk4, associates with D-cyclins to regulate cell proliferation. Following translocation to the nucleus, the Cdk6 is phosphorylated by CAK, and the Cdk6 complex, in association with PCNA, phosphorylates the retinoblastoma (Rb) protein. Overexpression of Cdk6 has been associated with several different types of cancer.Synonyms: Cell division protein kinase 6, PLSTIRE, Serine/threonine-protein kinase PLSTIRE

    基因ID

    1021

    NCBI登录号

    NP_001250

    UniProt

    Q00534

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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