SOCS5 抗体 (N-Term)
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北京 101111
Quick Overview for SOCS5 抗体 (N-Term) (ABIN488053)
抗原
See all SOCS5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-11, N-Term
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特异性
- Recognizes Suppressor of Cytokine Signaling 5 (SOCS5).
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Antigen-Affinity Chromatography.
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免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 11 of SOCS5.
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应用备注
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Western blotting: 1/500-1/3000. Immunohistochemistry on Paraffin Sections: 1/100-1/500. Positive Controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- 1 x PBS, 40 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at -20 °C.
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- SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))
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别名
- SOCS5 / CIS6
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背景
- The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.Synonyms: CIS-6, CISH5, CISH6, Cytokine-inducible SH2 protein 6, Cytokine-inducible SH2-containing protein 5, KIAA0671, SOCS-5, Suppressor of cytokine signaling 5
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基因ID
- 9655, 9606
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UniProt
- O75159
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途径
- JAK/STAT Signaling, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process
抗原
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