电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CCR4 抗体 (C-Term)

CCR4 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN488046
发货至: 中国
  • 抗原 See all CCR4 抗体
    CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
    抗原表位
    • 15
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 70
    • 29
    • 16
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 62
    • 8
    • 6
    克隆类型
    • 69
    • 6
    • 1
    多克隆
    标记
    • 41
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR4 antibody is un-conjugated
    应用范围
    • 45
    • 40
    • 17
    • 16
    • 14
    • 14
    • 13
    • 11
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Recognizes C-C Chemokine Receptor 4 (CCR4/CD194).
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Synthetic peptide – KLH conjugated. Epitope: C-terminal domain of Human.
    Top Product
    Discover our top product CCR4 Primary Antibody
  • 应用备注
    Immunohistochemistry on Paraffin Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer.
  • 抗原
    CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
    别名
    CD194 / CCR4 (CCR4 产品)
    别名
    CC-CKR-4 antibody, CD194 antibody, CKR4 antibody, CMKBR4 antibody, ChemR13 antibody, HGCN:14099 antibody, K5-5 antibody, Ccr4 antibody, C-C CKR-4 antibody, CHEMR1 antibody, Cmkbr4 antibody, LESTR antibody, Sdf1r antibody, C-C motif chemokine receptor 4 antibody, chemokine (C-C motif) receptor 4 antibody, CCR4 antibody, Ccr4 antibody
    背景
    Receptors for the C - C chemokine family include CCR1, CCR2A, CCR3, CCR4, CCR5 and the Duffy blood group antigen. The C - C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR4 is preferentially expressed on type 2 helper T (Th2-type) cells. In contrast to other chemokine receptors, the expression of CCR4 and CCR8 on Th2 cells is transiently increased following TCR and CD28 engagement. Moreover, activated Th1 cells up regulate CCR4 expression and functional responsiveness to thymus- and activation-regulated chemokine. CCR4 mediates inflammatory responses and HIV-1 infections. It binds beta-family chemokines (CC motif) such as TARC (thymus and activation-regulated chemokine) and MDC (macrophage-derived chemokine).Synonyms: C-C CKR-4, C-C chemokine receptor type 4, CC-CKR-4, CCR-4, CMKBR4, K5-5
    基因ID
    4887
    NCBI登录号
    NP_000901
    UniProt
    P51679
You are here:
客服