EYA1 抗体 (Internal Region)
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Quick Overview for EYA1 抗体 (Internal Region) (ABIN487975)
抗原
See all EYA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody reacts to EYA1.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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免疫原
- Peptide with sequence C-TDPTAEYSTIHSP, from the internal region of the protein sequence according to NP_742057.1, NP_000494.2, NP_742056.1.
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应用备注
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Peptide ELISA: 1/16000. Western blot: Approx 55 kDa band observed in lysates of cell lline HEK293 (calculated MWof 60.5 kDa according to NP_742056.1). Recommended concentration: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- EYA1 (Eyes Absent Homolog 1 (EYA1))
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别名
- EYA1
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背景
- EYA1 (Eyes Absent Homolog 1) is a member of the eyes absent (EYA) family of proteins. EYA1 plays a role in transcriptional regulation during organogenesis. It is thought play a role in the development of the kidney, branchial arches, eye and ear. EYA1 is thought to coactivate SIX2, SIX4 and SIX5. EYA1 has intrinsic protein phosphatase activity, and dephosphorylates proteins such as Histone H2.AX phosphorylated on Y142. It is thought to play a role in promoting efficient DNA repair over apoptosis in response to genotypic stress.Synonyms: Eyes absent homolog 1
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基因ID
- 2138
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NCBI登录号
- NP_000494
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UniProt
- Q99502
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途径
- Sensory Perception of Sound, Positive Regulation of Response to DNA Damage Stimulus
抗原
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