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CD44 抗体

This 小鼠 单克隆 antibody specifically detects CD44 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN487498
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD44 抗体 (ABIN487498)

抗原

See all CD44 抗体
CD44

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD44 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

156-3C11
  • 特异性

    This antibody is specific to a cell surface glycoprotein of 80-95 kDa, known as CD44, which is expressed on the surface of lymphocytes, monocytes, and granulocytes. This antibody reacts with red cells pretreated with 2-aminoethyl-isothiouronium bromide (AET).
    Cellular Localization: Cell membrane.

    产品特性

    Synonyms: CDw44, PGP-I, ECMR-III, Hermes antigen, Epican, LHR, MDU2, MDU3, MIC4, Phagocyticglycoprotein I, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesionreceptor, Hyaluronate receptor, Heparan sulfate proteoglycan

    纯化方法

    Purified

    免疫原

    BALB/C mice were injected with stimulated Human leukocytes.

    亚型

    IgG2a
  • 应用备注

    Immunohistochemistry and Paraffin Sections: Use at 1/25-1/75 in ABC method. Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Human tonsil.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD44

    别名

    CD44

    背景

    CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.Synonyms: CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein 1

    基因ID

    960

    UniProt

    P16070

    途径

    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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