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CD44 抗体 (FITC)

This anti-CD44 antibody is a 小鼠 单克隆 antibody detecting CD44 in FACS. Suitable for 人, 犬 和 Pig. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN457351
发货至: 中国

Quick Overview for CD44 抗体 (FITC) (ABIN457351)

抗原

See all CD44 抗体
CD44

适用

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人, 犬, Pig

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD44 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

MEM-263
  • 原理

    Anti-Hu CD44 FITC

    特异性

    The antibody MEM-263 reacts with extracellular (N-terminal) domain of standard CD44 (Phagocyte glycoprotein 1), a 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.), it is negative on platelets and hepatocytes.

    交叉反应 (详细)

    Human, Porcine, Canine (Dog)

    纯化方法

    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    COS-7 cells (African Green Monkey).

    亚型

    IgG1
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 溶解方式

    No reconstitution is necessary.

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.
    Avoid prolonged exposure to light.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Krešić, Prišlin, Vlahović, Kostešić, Ljolje, Brnić, Turk, Musulin, Habrun: "The Expression Pattern of Surface Markers in Canine Adipose-Derived Mesenchymal Stem Cells." in: International journal of molecular sciences, Vol. 22, Issue 14, (2021) (PubMed).

  • 抗原

    CD44

    别名

    CD44

    背景

    CD44 Molecule,CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.,PGP-I, HUTCH-I, ECMR-III, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican, MC56, MIC4, INLU, LHR

    基因ID

    960

    UniProt

    P16070

    途径

    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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