IL-8 抗体 (HRP)
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北京 101111
Quick Overview for IL-8 抗体 (HRP) (ABIN453903)
抗原
See all IL-8 (IL8) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes both, natural and recombinant IL-8. No cross-reactivity with human monocyte chemotactic activating factor (MCP-1) or RANTES (Regulated on Activation, Normal T-cell Expressed, and Secreted)
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纯化方法
- Affinity chromatography on Protein G
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免疫原
- Purified recombinant human IL-8 (monocyte-derive, 72-amino acid form)
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亚型
- IgG1
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应用备注
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01 M PBS, pH 7.0 ± 0.1 in 50 % Glycerol and 0.01 % thimerosal as a bacteriostat
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- IL-8 (IL8) (Interleukin 8 (IL8))
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别名
- Interleukin-8 / IL8
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背景
- IL8 is a member of the CXC chemokine family. This family of small basic heparan-binding proteins are proinflammatory and primarily mediate the activation and migration of neutrophils into tissue from peripheral blood. This chemokine is one of the major mediators of the inflammatory response and is secreted by several cell types in response to an inflammatory stimulus. It functions as a chemoattractant, and is also a potent angiogenic factor. IL8 attracts neutrophils, basophils, and T-cells, but not monocytes. Cystic fibrosis (CF) is characterized by severe lung inflammation. The inflammatory process is believed to be caused by massive overproduction of the proinflammatory protein IL8, and the high levels of IL8 in the CF lung are therefore believed to be the central mechanism behind CF lung pathophysiology.Synonyms: CXCL8, Emoctakin, GCP1, Granulocyte chemotactic protein 1, MDNCF, MONAP, Monocyte-derived neutrophil chemotactic factor, Monocyte-derived neutrophil-activating peptide, NAP1, Neutrophil-activating protein 1, Protein 3-10C, T-cell chemotactic factor
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基因ID
- 3576
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NCBI登录号
- NP_000575
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UniProt
- P10145
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途径
- TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
抗原
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