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IL-8 抗体 (Biotin)

The 小鼠 单克隆 anti-IL-8 antibody is suitable to detect IL-8 in samples from 人. It has been validated for EIA.
产品编号 ABIN453902
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL-8 抗体 (Biotin) (ABIN453902)

抗原

See all IL-8 (IL8) 抗体
IL-8 (IL8) (Interleukin 8 (IL8))

适用

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小鼠

克隆类型

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单克隆

标记

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This IL-8 antibody is conjugated to Biotin

应用范围

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Enzyme Immunoassay (EIA)

克隆位点

I8-60
  • 特异性

    This antibody recognizes both, native and recombinant Human IL-8. No cross-reactivity with human monocyte chemotactic activating factor (MCP-1) or RANTES (Regulated on Activation, Normal T-cell Expressed, and Secreted).

    纯化方法

    Affinitty chromatography on Protein G

    免疫原

    Purified recombinant human IL-8 (monocyte-derive, 72-amino acid form)

    亚型

    IgG1
  • 应用备注

    ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.01 M PBS, pH 7.2, 0.1 % Proclin-300, 1 % Gelatin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    IL-8 (IL8) (Interleukin 8 (IL8))

    别名

    Interleukin-8 / IL8

    背景

    IL8 is a member of the CXC chemokine family. This family of small basic heparan-binding proteins are proinflammatory and primarily mediate the activation and migration of neutrophils into tissue from peripheral blood. This chemokine is one of the major mediators of the inflammatory response and is secreted by several cell types in response to an inflammatory stimulus. It functions as a chemoattractant, and is also a potent angiogenic factor. IL8 attracts neutrophils, basophils, and T-cells, but not monocytes. Cystic fibrosis (CF) is characterized by severe lung inflammation. The inflammatory process is believed to be caused by massive overproduction of the proinflammatory protein IL8, and the high levels of IL8 in the CF lung are therefore believed to be the central mechanism behind CF lung pathophysiology.Synonyms: CXCL8, Emoctakin, GCP1, Granulocyte chemotactic protein 1, MDNCF, MONAP, Monocyte-derived neutrophil chemotactic factor, Monocyte-derived neutrophil-activating peptide, NAP1, Neutrophil-activating protein 1, Protein 3-10C, T-cell chemotactic factor

    基因ID

    3576

    NCBI登录号

    NP_000575

    UniProt

    P10145

    途径

    TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
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