BMI1 抗体
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北京 101111
Quick Overview for BMI1 抗体 (ABIN453535)
抗原
See all BMI1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to BMI-1 / RNF51.
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- BMI1 recombinant protein
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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别名
- BMI-1 / RNF51
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背景
- Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.Synonyms: BMI1, PCGF4, Polycomb group RING finger protein 4, RING finger protein 51
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基因ID
- 648
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NCBI登录号
- NP_005171
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UniProt
- P35226
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途径
- Cell Division Cycle, Autophagy
抗原
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