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TDG 抗体 (C-Term)

This anti-TDG antibody is a 兔 多克隆 antibody detecting TDG in WB 和 EIA. Suitable for 人.
产品编号 ABIN453411
发货至: 中国
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Quick Overview for TDG 抗体 (C-Term) (ABIN453411)

抗原

See all TDG 抗体
TDG (Thymine-DNA Glycosylase (TDG))

适用

  • 51
  • 20
  • 12
  • 2
  • 1

宿主

  • 39
  • 12

克隆类型

  • 42
  • 10
多克隆

标记

  • 45
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TDG antibody is un-conjugated

应用范围

  • 40
  • 15
  • 13
  • 9
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    C-Term

    特异性

    This antibody reacts to TDG.

    纯化方法

    Saturated Ammonium Sulfate (SAS) precipitation

    免疫原

    KLH conjugated synthetic peptide selected from the C-terminal region of human TDG
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TDG (Thymine-DNA Glycosylase (TDG))

    别名

    TDG

    背景

    The protein TDG belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine.Synonyms: G/T mismatch-specific thymine DNA glycosylase

    基因ID

    6996

    NCBI登录号

    NP_003202

    UniProt

    Q13569

    途径

    DNA Damage Repair, Chromatin Binding
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