TDG 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for TDG 抗体 (C-Term) (ABIN453411)
抗原
See all TDG 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- This antibody reacts to TDG.
-
纯化方法
- Saturated Ammonium Sulfate (SAS) precipitation
-
免疫原
- KLH conjugated synthetic peptide selected from the C-terminal region of human TDG
-
-
-
-
应用备注
-
ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS with 0.09 % (W/V) sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- TDG (Thymine-DNA Glycosylase (TDG))
-
别名
- TDG
-
背景
- The protein TDG belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine.Synonyms: G/T mismatch-specific thymine DNA glycosylase
-
基因ID
- 6996
-
NCBI登录号
- NP_003202
-
UniProt
- Q13569
-
途径
- DNA Damage Repair, Chromatin Binding
抗原
-