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TBP 抗体 (C-Term)

Name: TBP 抗体 (C-Term)
SKU: ABIN453409
Availability: OutOfStock

TBP 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of TBP antibody (C-term) in HL60 cell line lysates (35ug/lane). (TBP 抗体 (C-Term))

1 image

产品编号 ABIN453409

发货至: 中国

Datasheet as PDF

抗原 See all TBP 抗体

TBP (TATA Box Binding Protein (TBP))
抗原表位
15

6

5

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
68

41

39

6

6

5

5

4

4

3

3

3

3

2

2

1

1
人
宿主
50

18

2
兔
Compatible Secondaries
克隆类型
50

20
多克隆
标记
50

3

3

3

1

1

1

1

1

1

1

1

1

1

1
This TBP antibody is un-conjugated
应用范围
63

27

14

13

13

11

11

9

7

5

4

2

1

1

1

1

1

1

1
Western Blotting (WB), Enzyme Immunoassay (EIA)

特异性

This antibody reacts to TBP (TATA-box-binding protein).

纯化方法

Saturated Ammonium Sulfate (SAS) precipitation

免疫原

KLH conjugated synthetic peptide selected from the C-terminal region of human TBP

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anti-TATA Box Binding Protein (TBP) (N-Term) antibody
TBP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-TATA Box Binding Protein (TBP) (AA 39-50) antibody
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TBP 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB20259 unconjugated

anti-TATA Box Binding Protein (TBP) antibody
TBP 适用: 人, 小鼠, 大鼠, Cynomolgus WB, IHC (p), IF (cc) 宿主: 小鼠 Monoclonal 8C4 unconjugated

anti-TATA Box Binding Protein (TBP) (AA 8-316) antibody
TBP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA: 1/1,000. Western blot: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

浓度

0.25 mg/mL

缓冲液

PBS with 0.09 % (W/V) sodium azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

TBP (TATA Box Binding Protein (TBP))

别名

TBP (TATA-Box-Binding Protein) (TBP 产品)

别名

GTF2D antibody, GTF2D1 antibody, HDL4 antibody, SCA17 antibody, TFIID antibody, Gtf2d antibody, fd20h06 antibody, si:zc101n13.2 antibody, wu:fd20h06 antibody, zgc:66213 antibody, TBP1 antibody, TBP antibody, tbp antibody, CG9874 antibody, Dmel\\CG9874 antibody, RBP antibody, TBP38 antibody, TFIIDtau antibody, TfIID antibody, dTBP antibody, dTFIID antibody, dTbp antibody, dtbp antibody, gtf2d antibody, gtf2d1 antibody, sca17 antibody, tfiid antibody, tfiidtau antibody, xtbp antibody, tbp-a antibody, tbp-b antibody, TATA-box binding protein antibody, TATA box binding protein antibody, TATA binding protein antibody, TATA-box binding protein L homeolog antibody, TATA-box-binding protein antibody, TATA-box binding protein S homeolog antibody, TBP antibody, Tbp antibody, tbp antibody, tbp.L antibody, tbp.S antibody

背景

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. A distinctive feature of TBP is a long string of glutamines in the N-terminal. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. Mutations that expand the number of CAG repeats encoding this polyglutamine tract, and thus increase the length of the polyglutamine string, are associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.Synonyms: GTF2D1, TATA-binding factor, TATA-box factor, TF2D, TFIID, Transcription initiation factor TFIID TBP subunit

基因ID

6908

NCBI登录号

NP_003185

UniProt

P20226

途径

WNT signaling