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SETD8 抗体 (Middle Region)

SETD8 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN453371
发货至: 中国
  • 抗原 See all SETD8 抗体
    SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
    抗原表位
    • 22
    • 8
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 64
    • 22
    • 11
    宿主
    • 48
    • 16
    克隆类型
    • 47
    • 17
    多克隆
    标记
    • 28
    • 8
    • 6
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SETD8 antibody is un-conjugated
    应用范围
    • 51
    • 36
    • 23
    • 9
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to SETD8.
    纯化方法
    Saturated Ammonium Sulfate (SAS) precipitation
    免疫原
    KLH conjugated synthetic peptide selected from the Center region of human SETD8
    Top Product
    Discover our top product SETD8 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
    别名
    SETD8 / SET07 (SETD8 产品)
    背景
    SETD8 is a histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4. H4 'Lys-20' monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. It is required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. It is also involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones.Synonyms: H4-K20-HMTase SETD8, Histone-lysine N-methyltransferase SETD8, KMT5A, Lysine N-methyltransferase 5A, PR-Set7, PR/SET domain-containing protein 07, PRSET7, SET domain-containing protein 8, SET8
    基因ID
    387893
    NCBI登录号
    NP_065115
    UniProt
    Q9NQR1
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