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HSPD1 抗体 (N-Term)

Name: HSPD1 抗体 (N-Term)
SKU: ABIN453118
Availability: OutOfStock

This anti-HSPD1 antibody is a 兔多克隆 antibody detecting HSPD1 in WB 和 EIA. Suitable for 人和小鼠.

Western blot analysis of Hsp 60 Antibody (N-term) in mouse lung tissue lysates (35ug/lane). (HSPD1 抗体 (N-Term))

1 image

产品编号 ABIN453118

发货至: 中国

Quick Overview for HSPD1 抗体 (N-Term) (ABIN453118)

抗原

See all HSPD1 抗体

HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This HSPD1 antibody is un-conjugated

应用范围

Western Blotting (WB), Enzyme Immunoassay (EIA)

Discover our top product HSPD1 Primary Antibody

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N-Term

特异性

This antibody reacts to Hsp 60.

纯化方法

Saturated Ammonium Sulfate (SAS) precipitation

免疫原

KLH conjugated synthetic peptide selected from the N-terminal region of human Hsp60
anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) (AA 501-573) antibody
HSPD1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) (AA 27-240) antibody
HSPD1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) antibody
HSPD1 适用: 人 WB, IHC, FACS, ELISA, IP 宿主: 小鼠 Monoclonal LK1 unconjugated

anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) antibody
HSPD1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 3G8 unconjugated

anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) (AA 1-573) antibody
HSPD1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) (AA 172-343) antibody
HSPD1 适用: 人 WB, IHC, FACS, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) (AA 316-573) antibody
HSPD1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) antibody
HSPD1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IEM 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) (AA 1-573) antibody
HSPD1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1) antibody
HSPD1 适用: 人, 小鼠, 大鼠, 小鸡, 猴, Hamster, 犬, Cow, 兔, Pig, 绵羊, Drosophila melanogaster, 非洲爪蟾 WB, IHC, IF, FACS, ISt, StM 宿主: 小鼠 Monoclonal LK1 unconjugated

应用备注

ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

浓度

0.25 mg/mL

缓冲液

PBS with 0.09 % (W/V) sodium azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))

别名

HSP60

背景

Hsp60 is a member of a highly conserved family which includes molecular chaperones from several species such as plant Hsp60 (known as Rubisco binding protein), GroEL, the E.coli Hsp60 and 65 kDa major antigen of mycobacteria. In eukaryotes, Hsp60 is localized in the mitochondrial matrix and in plants Hsp60 is localized in the chloroplast. Mitochondria, chloroplasts and bacteria have a common ancestry (>1 billion years) and this fact together with the high degree of homology between the divegent Hsp60s would indicate that these proteins carry out a primitive but important function which is similar to all of these different species.The common characteristics of the Hsp60s from the divergent species are i) high abundance, ii) induction with environmental stress such as heat shock, iii) homo oligomeric structures of either 7 or 14 subunits which reversibly dissociate in the presence of magnesium ions and ATP, iv) ATPase activity and v) a role in folding and assembly of oligomeric protein structures. These similarities are supported by recent studies where the single ring human mitochondrial homolog, Hsp60 with its co chaperonin, Hsp10 were expressed in a E. coli strain, engineered so that the groE operon is under strict regulatory control. This study has demonstrated that expression of Hsp60-Hsp10 was able to carry out all essential in vivo functions of GroEL and its co chaperonin, GroES. Consistent with their functions as chaperones, Hsp60 and Hsp10 have been suggested to act as docking molecules with a passive role in the maturation of caspase processing. Data demonstrates that recombinant Hsp60 and Hsp10 have been shown to accelerate the activation of procaspase 3 by cytochrome c and dATP in an ATP dependent manner. Hsps are intracellular proteins which are thought to serve protective functions against infection and cellular stress, however several recent studies indicate that members of the Hsp60 family are linked to a number of autoimmune diseases, artherosclerosis and chlamydial disease.Synonyms: 60 kDa chaperonin, 60 kDa heat shock protein mitochondrial, CPN60, Chaperonin 60, GROEL, GroEL Homolog, HSP-60, HSPD1, Heat shock protein 60, HuCHA60, Mitochondrial matrix protein P1, P60 lymphocyte protein

基因ID

3329

NCBI登录号

NP_002147

UniProt

P10809

途径

Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity