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CREB1 抗体 (pSer133)

CREB1 适用: 人 EIA 宿主: 小鼠 Monoclonal B1C4 unconjugated
产品编号 ABIN452620
发货至: 中国
  • 抗原 See all CREB1 抗体
    CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))
    抗原表位
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    pSer133
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CREB1 antibody is un-conjugated
    应用范围
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    Enzyme Immunoassay (EIA)
    特异性
    Reactive to serine133 phosphorylated Human CREB peptide fragment, and reactive to KLH or BSA conjugated Serine133 phosphorylated Human CREB peptide fragment. Not reactive to un-conjugated KLH or BSA.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    产品特性
    Synonyms: CREB-1, Cyclic AMP-responsive element-binding protein 1, cAMP-responsiveelement-binding protein 1
    纯化方法
    Affinity Chromatography on Protein G.
    免疫原
    Phosphorylated peptide fragment of CREB (pSer133), conjugated with KLH
    克隆位点
    B1C4
    亚型
    IgG2b
    Top Product
    Discover our top product CREB1 Primary Antibody
  • 应用备注
    Indirect ELISA: The suggested antigen coating quantity is 1 μg/mL of peptide/or peptideconjugating in pH 9.5 Carbonate buffer, 100 μL/well.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.
    缓冲液
    0.01 M PBS, pH 7.0 without preservatives.
    储存液
    Without preservative
    储存条件
    -20 °C
    储存方法
    Store the antibody at -20 °C. After reconstitution, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))
    别名
    CREB1 (CREB1 产品)
    别名
    creb antibody, CREB1 antibody, Creb1 antibody, CREB antibody, 2310001E10Rik antibody, 3526402H21Rik antibody, AV083133 antibody, Creb antibody, Creb-1 antibody, creb1 antibody, zgc:55598 antibody, cAMP responsive element binding protein 1 antibody, cAMP responsive element binding protein antibody, cAMP responsive element binding protein 1 S homeolog antibody, cAMP responsive element binding protein 1a antibody, CREB1 antibody, creb1 antibody, CREB antibody, Creb1 antibody, creb1.S antibody, creb1a antibody
    背景
    Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity. Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1. CREB appears to play an important role in learning and memory in both flies and mice.Synonyms: CREB-1, Cyclic AMP-responsive element-binding protein 1, cAMP-responsive element-binding protein 1
    基因ID
    1385
    UniProt
    P16220
    途径
    TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
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