L-Selectin 抗体
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- 抗原 See all L-Selectin (SELL) 抗体
- L-Selectin (SELL) (Selectin L (SELL))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This L-Selectin antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- 特异性
- This antibody recognizes CD62L / L-selectin, a 65-76 kDa cell surface protein, expressed by neutrophils, monocytes, and subsets of T, B, and NK cells, that interacts with specific carbohydrates exposed on activated endothelial cells.
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 产品特性
- Synonyms: SELL, LNHR, LYAM1, Leu-8, TQ1, gp90-MEL, LECAM1, LAM-1, Lymph node homing receptor,Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelialcell adhesion molecule 1, CD62 antigen-like family member L
- 纯化方法
- Protein A Affinity Chromatography
- 免疫原
- PMA-activated human peripheral blood leukocytes
- 克隆位点
- DREG56
- 亚型
- IgG1
- Top Product
- Discover our top product SELL Primary Antibody
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anti-Selectin L (SELL) (AA 301-372) antibody
SELL 适用: 小鼠, 大鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Selectin L (SELL) (AA 1-100) antibodySELL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Selectin L (SELL) antibody (APC)SELL 适用: 人 FACS 宿主: 小鼠 Monoclonal LT-TD180 APC
anti-Selectin L (SELL) (AA 83-186) antibodySELL 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 8C8B7 unconjugated
anti-Selectin L (SELL) (AA 109-346) antibodySELL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Selectin L (SELL) antibodySELL 适用: 人, Cow FACS, IP, ICC 宿主: 小鼠 Monoclonal IVA94 unconjugated
anti-Selectin L (SELL) antibody (FITC)SELL 适用: 人 FACS 宿主: 小鼠 Monoclonal DREG56 FITC
anti-Selectin L (SELL) antibodySELL 适用: 小鼠 FACS, IP, IHC (fro), ICC, IHC (p) 宿主: 大鼠 Monoclonal Mel-14 unconjugated
anti-Selectin L (SELL) antibodySELL 适用: 小鼠 FACS, IP, IHC (fro), Func, ICC, IHC (p) 宿主: 大鼠 Monoclonal Mel-14 unconjugated
anti-Selectin L (SELL) antibody (FITC)SELL 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal Mel-14 FITC
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- 应用备注
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Flow cytometry: 2 μg/mL. Immunoprecipitation. Western blot (non-reducing conditions). Immunohistochemistry on frozen sections. Functional application: Particularly effective in blocking of lymphocyte CD62L-mediatedbinding to peripheral lymph node HEV.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.4 with 15 mM Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- L-Selectin (SELL) (Selectin L (SELL))
- 别名
- CD62L / L-Selectin (SELL 产品)
- 物质类
- Chemical
- 背景
- CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1). The level of CD62L expression can be used to help distinguish naive T cells from effector/memory T cells.Synonyms: CD62 antigen-like family member L, LAM-1, LECAM1, LNHR, LYAM1, Leu-8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, Lymph node homing receptor, SELL, TQ1, gp90-MEL
- 基因ID
- 6402
- UniProt
- P14151
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