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SHP1 抗体

PTPN6 适用: 人 WB, IF, IHC (fro), EIA 宿主: 小鼠 Monoclonal PTY15 unconjugated
产品编号 ABIN452175
发货至: 中国
  • 抗原 See all SHP1 (PTPN6) 抗体
    SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
    适用
    • 113
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    宿主
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    小鼠
    克隆类型
    • 96
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    单克隆
    标记
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    This SHP1 antibody is un-conjugated
    应用范围
    • 83
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes single 67 kDa PTP1-C in Human cells that express the enzyme and the SH2(C) domain
    产品特性
    Synonyms: PTPN-6, HCP, PTP1C, EC=3.1.3.48, Protein-tyrosine phosphatase 1C, PTP-1C, SH-PTP1,Protein-tyrosine phosphatase SHP-1, Hematopoietic cell protein-tyrosine phosphatase,Tyrosine-protein phosphatase non-receptor type 6
    纯化方法
    Affinity chromatography on Protein G
    免疫原
    Purified recombinant protein corresponding to full-length PTP1-C
    克隆位点
    PTY15
    亚型
    IgG1
    Top Product
    Discover our top product PTPN6 Primary Antibody
  • 应用备注
    ELISA. Western Blot. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.
    缓冲液
    0.01 M PBS, pH 7.2 without preservatives
    储存液
    Without preservative
    储存条件
    -20 °C
    储存方法
    Prior to and following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
    别名
    PTPN6 (PTPN6 产品)
    别名
    HCPH antibody, HPTP1C antibody, PTP-1C antibody, SH-PTP1 antibody, SHP-1 antibody, SHP-1L antibody, SHP1 antibody, DRPLA antibody, Hcph antibody, Ptp1C antibody, me antibody, motheaten antibody, Ptph6 antibody, Shp-1 antibody, fj22f05 antibody, wu:fj22f05 antibody, zgc:55501 antibody, ptpn6 antibody, protein tyrosine phosphatase, non-receptor type 6 antibody, protein tyrosine phosphatase, non-receptor type 6 L homeolog antibody, PTPN6 antibody, Ptpn6 antibody, ptpn6 antibody, ptpn6.L antibody
    背景
    The phosphorylation state of receptors and signal transduction molecules influences almost every cell activities. The phosphorylation rate is regulated by kinases which add phosphate group and by phosphatases which remove phosphate group form the amino acid residues on protein molecules. Protein tyrosine phosphatase 1 C (PTP1C) is a tyrosine phosphatase highly expressed in heomatopoietic cells. PTP1C was found to co-precipitate with B lymphocytespecific cell surface glycoprotein CD22, after anti-immunoglobulin stimulation. Study with PTP1C deficient mice showed that the phosphatase may implicate with negative selection in B cell immunity.Synonyms: HCP, Hematopoietic cell protein-tyrosine phosphatase, PTP-1C, PTP1C, PTPN-6, Protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6
    基因ID
    5777
    UniProt
    P29350
    途径
    JAK/STAT Signaling, TCR Signaling, TLR signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling
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