SHP1 抗体
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北京 101111
Quick Overview for SHP1 抗体 (ABIN452174)
抗原
See all SHP1 (PTPN6) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes single 67 kDa PTP1-C in Human cells that express the enzyme and the SH2(C) domain.
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产品特性
- Synonyms: PTPN-6, HCP, PTP1C, EC=3.1.3.48, Protein-tyrosine phosphatase 1C, PTP-1C, SH-PTP1,Protein-tyrosine phosphatase SHP-1, Hematopoietic cell protein-tyrosine phosphatase,Tyrosine-protein phosphatase non-receptor type 6
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纯化方法
- Affinity chromatography on Protein G
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免疫原
- Purified recombinant protein corresponding to full-length PTP1-C
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亚型
- IgG1
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anti-Protein-tyrosine Phosphatase 1C (PTPN6) antibody
PTPN6 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) antibodyPTPN6 适用: 人 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal CPTC-APEX1-2 unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) antibodyPTPN6 适用: 人 WB, IHC (p), IP, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-595) antibodyPTPN6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 243-541) antibodyPTPN6 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2E9E4 unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 100-400) antibodyPTPN6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 1-597), (Isoform 2) antibodyPTPN6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) (pTyr536) antibodyPTPN6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) (C-Term) antibodyPTPN6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 247-277) antibodyPTPN6 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17225 unconjugated
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应用备注
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ELISA. Western Blot. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.
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缓冲液
- 0.01 M PBS, pH 7.2 without preservatives
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Prior to and following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
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别名
- PTPN6
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背景
- The phosphorylation state of receptors and signal transduction molecules influences almost every cell activities. The phosphorylation rate is regulated by kinases which add phosphate group and by phosphatases which remove phosphate group form the amino acid residues on protein molecules. Protein tyrosine phosphatase 1 C (PTP1C) is a tyrosine phosphatase highly expressed in heomatopoietic cells. PTP1C was found to co-precipitate with B lymphocytespecific cell surface glycoprotein CD22, after anti-immunoglobulin stimulation. Study with PTP1C deficient mice showed that the phosphatase may implicate with negative selection in B cell immunity.Synonyms: HCP, Hematopoietic cell protein-tyrosine phosphatase, PTP-1C, PTP1C, PTPN-6, Protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6
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基因ID
- 5777
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UniProt
- P29350
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途径
- JAK/STAT Signaling, TCR Signaling, TLR signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling
抗原
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