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EGFR 抗体 (Tyr1197)
EGFR
适用: 人, 小鼠, 大鼠
WB
宿主: 兔
Polyclonal
unconjugated
EGFR抗体详情
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抗原
See all EGFR 抗体
EGFR
(Epidermal Growth Factor Receptor (EGFR))
抗原表位
All epitopes for EGFR 抗体
Tyr1197
适用
All reactivities for EGFR 抗体
人, 小鼠, 大鼠
宿主
All hosts for EGFR 抗体
兔
克隆类型
All clonalities for EGFR 抗体
多克隆
标记
All conjugates for EGFR 抗体
This EGFR antibody is un-conjugated
应用范围
All applications for EGFR 抗体
Western Blotting (WB)
特异性
EGFR goat polyclonal antibody detects endogenous levels of total EGFR protein.
纯化方法
Affinity chromatography
免疫原
Synthesized non-phosphopeptide derived from human EGFR around the phosphorylation site of tyrosine 1197 (A-E-YP-L-R)
Top Product
Discover our top product EGFR Primary Antibody
Alternatives
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anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR
适用: 人, 小鼠, 大鼠, 猴, Pig, Cow, 小鸡, 犬, 马, 兔, 豚鼠, Avian, Cat, 驴, 山羊, Hamster, 绵羊
WB
宿主: 山羊
Polyclonal
unconjugated
使用细节
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应用备注
Western Blot: 1/500 - 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
贮存及处理
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浓度
1,0 mg/mL
缓冲液
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C
EGFR目标详情
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抗原
EGFR
(Epidermal Growth Factor Receptor (EGFR))
别名
EGFR / ERBB1 (EGFR 产品 )
别名
C-erb antibody, CG10079 antibody, D-EGFR antibody, D-Egf antibody, DEGFR antibody, DER antibody, DER flb antibody, DER/EGFR antibody, DER/faint little ball antibody, DER/top antibody, DER/torpedo antibody, DER1 antibody, DEgfr antibody, Degfr antibody, Der antibody, DmHD-33 antibody, Dmel\\CG10079 antibody, EFG-R antibody, EGF-R antibody, EGFR antibody, EGFr antibody, EGfr antibody, EK2-6 antibody, Egf antibody, Egf-r antibody, EgfR antibody, El antibody, Elp antibody, Elp-1 antibody, Elp-B1 antibody, Elp-B1RB1 antibody, HD-33 antibody, TOP antibody, Torpedo/DER antibody, Torpedo/Egfr antibody, c-erbB antibody, d-egf-r antibody, dEGFR antibody, dEGFR1 antibody, dEgfr antibody, der antibody, egfr antibody, flb antibody, l(2)05351 antibody, l(2)09261 antibody, l(2)57DEFa antibody, l(2)57EFa antibody, l(2)57Ea antibody, mor1 antibody, top antibody, top/DER antibody, top/flb antibody, torpedo/Egfr antibody, torpedo/egfr antibody, EGFR12 antibody, EGFR15 antibody, egfr1 antibody, Erbb2 antibody, ERBB antibody, ERBB1 antibody, HER1 antibody, PIG61 antibody, mENA antibody, ErbB-1 antibody, Errp antibody, 9030024J15Rik antibody, AI552599 antibody, Erbb antibody, Errb1 antibody, Wa5 antibody, wa-2 antibody, wa2 antibody, epidermal growth factor receptor antibody, Epidermal growth factor receptor antibody, epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) antibody, EGFR antibody, Egfr antibody, egfra antibody, egfr1 antibody, LOC5564544 antibody
背景
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.Synonyms: EGF Receptor, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, c-ErbB-1, erbB-1
基因ID
1956
NCBI登录号
NP_005219
UniProt
P00533
途径
NF-kappaB Signaling , RTK signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Stem Cell Maintenance , Hepatitis C , Positive Regulation of Response to DNA Damage Stimulus , Interaction of EGFR with phospholipase C-gamma , Thromboxane A2 Receptor Signaling , EGFR Downregulation , S100 Proteins
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