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SERPINB2 抗体 (Internal Region)

SERPINB2 适用: 人, 灵长类 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN401463
发货至: 中国
  • 抗原 See all SERPINB2 抗体
    SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
    抗原表位
    • 15
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 40
    • 12
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    人, 灵长类
    宿主
    • 41
    • 6
    • 1
    • 1
    克隆类型
    • 45
    • 3
    多克隆
    标记
    • 28
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SERPINB2 antibody is un-conjugated
    应用范围
    • 28
    • 18
    • 13
    • 13
    • 11
    • 7
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody is directed against PAI-2 protein.
    交叉反应 (详细)
    Species reactivity (expected):Primates.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    免疫原
    Peptide corresponding to an internal area of human PAI-2 protein
    亚型
    IgG
    Top Product
    Discover our top product SERPINB2 Primary Antibody
  • 应用备注
    ELISA: 1/100,000 - 1/150,000. Western Blot: 1/500 - 1/2,000
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.2 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
    别名
    SERPINB2 / PAI2 (SERPINB2 产品)
    别名
    HsT1201 antibody, PAI antibody, PAI-2 antibody, PAI2 antibody, PLANH2 antibody, SERPINB2 antibody, Planh2 antibody, ovalbumin antibody, Pai2a antibody, serpin family B member 2 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 2 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 2 antibody, SERPINB2 antibody, Serpinb2 antibody
    物质类
    Amino Acid
    背景
    Extracellular plasminogen activator inhibitor type-2 (also known as PAI-2, Placental plasminogen activator inhibitor, Monocyte Arg-serpin, Urokinase inhibitor, SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2) is a coagulation factor and a potent inhibitor of urokinase-type plasminogen activator (u-PA) and also acts as a multifunctional protein. It is present in most cells, especially monocytes and macrophages. PAI-2 exists in two forms, a 60- kDa, secreted, extracellular, glycosylated form and a 43- kDa intracellular form. It is a multifunctional protein that plays a role in cell differentiation, in prevention of programmed cell death, in the regulation of cell proliferation, in the inhibition of microbial proteinases and in the protection against stromal degradation. High levels of the PAI-2 protein are associated with a good prognosis in breast cancer, small cell lung, ovarian cancer, and inhibition of metastasis. PAI-2 also plays a role in inflammation on the surface of the eye. PAI-2 may cooperate with pRb2/p130 in modulating PAI-2 gene expression by chromatin remodeling.Synonyms: Monocyte Arg-serpin, PAI-2, PLANH2, Placental plasminogen activator inhibitor, Plasminogen activator inhibitor 2, Serpin B2, Urokinase inhibitor
    基因ID
    5055
    NCBI登录号
    NP_001137290
    UniProt
    P05120
    途径
    Autophagy
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