SERPINB2 抗体 (Internal Region)
Quick Overview for SERPINB2 抗体 (Internal Region) (ABIN401463)
抗原
See all SERPINB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- This antibody is directed against PAI-2 protein.
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交叉反应 （详细）
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Species reactivity (expected):Primates.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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免疫原
- Peptide corresponding to an internal area of human PAI-2 protein
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亚型
- IgG
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anti-Plasminogen Activator Inhibitor 2 (SERPINB2) antibody
SERPINB2 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (Center) antibodySERPINB2 适用: 人, 小鼠 WB, IP, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 154-408) antibodySERPINB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A10 unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-100) antibodySERPINB2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 154-408) antibodySERPINB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 293-389) antibodySERPINB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415) antibodySERPINB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (Internal Region) antibodySERPINB2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 170-393) antibodySERPINB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 116-144) antibodySERPINB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19097 unconjugated
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应用备注
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ELISA: 1/100,000 - 1/150,000. Western Blot: 1/500 - 1/2,000
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.2 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
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别名
- SERPINB2 / PAI2
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物质类
- Amino Acid
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背景
- Extracellular plasminogen activator inhibitor type-2 (also known as PAI-2, Placental plasminogen activator inhibitor, Monocyte Arg-serpin, Urokinase inhibitor, SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2) is a coagulation factor and a potent inhibitor of urokinase-type plasminogen activator (u-PA) and also acts as a multifunctional protein. It is present in most cells, especially monocytes and macrophages. PAI-2 exists in two forms, a 60- kDa, secreted, extracellular, glycosylated form and a 43- kDa intracellular form. It is a multifunctional protein that plays a role in cell differentiation, in prevention of programmed cell death, in the regulation of cell proliferation, in the inhibition of microbial proteinases and in the protection against stromal degradation. High levels of the PAI-2 protein are associated with a good prognosis in breast cancer, small cell lung, ovarian cancer, and inhibition of metastasis. PAI-2 also plays a role in inflammation on the surface of the eye. PAI-2 may cooperate with pRb2/p130 in modulating PAI-2 gene expression by chromatin remodeling.Synonyms: Monocyte Arg-serpin, PAI-2, PLANH2, Placental plasminogen activator inhibitor, Plasminogen activator inhibitor 2, Serpin B2, Urokinase inhibitor
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基因ID
- 5055
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NCBI登录号
- NP_001137290
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UniProt
- P05120
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途径
- Autophagy
抗原
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