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MARK2 抗体 (Isoform A, pThr595)

The 兔 多克隆 anti-MARK2 antibody is suitable to detect MARK2 in samples from 人, 小鼠, 大鼠, Cow 和 犬. It has been validated for WB 和 EIA.
产品编号 ABIN401318
发货至: 中国
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Quick Overview for MARK2 抗体 (Isoform A, pThr595) (ABIN401318)

抗原

See all MARK2 抗体
MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

适用

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人, 小鼠, 大鼠, Cow, 犬

宿主

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  • 3
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克隆类型

  • 64
  • 21
多克隆

标记

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This MARK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Isoform A, pThr595

    特异性

    This antibody is directed against the phosphorylated form of MARK2 at thepT595 residue.

    交叉反应 (详细)

    Species reactivity (expected):Canine, Bovine, Mouse, Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    免疫原

    Synthetic peptide corresponding to amino acids surrounding T595 of Human MARK2 isoform a. The immunogen peptide was phosphorylated at the residue corresponding to T595

    亚型

    IgG
  • 应用备注

    ELISA: 1/1,000 - 1/3,000. Western Blot: 1/250 - 1/1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.6 mg/mL (by UV absorbance at 280 nm)

    缓冲液

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C
  • 抗原

    MARK2 (MAP/microtubule Affinity-Regulating Kinase 2 (MARK2))

    别名

    MARK2

    背景

    This antibody recognizes a regulatory phosphorylation on a kinase that is critical to regulation of microtubules, cell cycle and immune responses. MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encode two isoforms of the human ser/thr protein kinase EMK1 called MARK2. These isoforms were characterized by the presence of a 162-bp alternative exon that gives rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be co-expressed in a number of selected cell lines and tissue samples. Human MARK2 was shown to be encoded by a single mRNA that is ubiquitously expressed. This transcription variant includes the alternative exon in the coding region and therefore codes for a longer protein. Multiple splice variants exist for this protein.Synonyms: 2, ELKL motif kinase, EMK1, MAP/microtubule affinity-regulating kinase, MARK2, PAR1 homolog, Serine/threonine-protein kinase

    基因ID

    2011

    NCBI登录号

    NP_001034558

    UniProt

    Q7KZI7

    途径

    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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