JAG1 抗体 (AA 110-125)
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Quick Overview for JAG1 抗体 (AA 110-125) (ABIN401024)
抗原
See all JAG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 110-125
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特异性
- This protein A purified antibody is directed against Human Jagged-1 protein. Expect a band approximately 150 kDa in size corresponding to Jagged-1 in Mouse liver whole cell lysates, and a 75 kDa band in Human brain and kidney lysates. A BLAST analysis was used to suggest cross reactivity with Jagged-1 protein from Human, Chimpanzee, Rat and Mouse based on 100 % homology with the immunizing sequence. Partial reactivity is expected against dog (81 %) and Xenopus laevis (85 %) based on partial sequence homologies as indicated. Reactivity against homologues from other sources is not known.
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交叉反应 （详细）
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Species reactivity (expected):Chimpanzee, Rat.
Species reactivity (tested):Human and Mouse. -
纯化方法
- Affinity Chromatography on Protein A.
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免疫原
- Synthetic peptide corresponding to amino acids 110-125 of Human Jagged-1 protein.
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亚型
- IgG
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anti-Jagged 1 (JAG1) (N-Term) antibody
JAG1 适用: 人, 小鼠 WB, IHC, ELISA, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 47-212) antibodyJAG1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 7C7H2 unconjugated
anti-Jagged 1 (JAG1) (Internal Region) antibodyJAG1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 47-212) antibodyJAG1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6A9B2 unconjugated
anti-Jagged 1 (JAG1) (AA 836-1047) antibodyJAG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 809-1046) antibodyJAG1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) antibodyJAG1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal J1G53-3 unconjugated
anti-Jagged 1 (JAG1) (AA 826-1084) antibodyJAG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 470-834) antibodyJAG1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 33-250) antibodyJAG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Suitable for use in ELISA, Immunohistochemistry, Immunofluorescence microscopy andWestern blot. Recommended Dilutions: ELISA: 1/20,000-1/100,000. Western Blot: 1/500-1/2,000. Immunofluorescence: 1/200-1/1,000. Immunohistochemistry on Paraffin Sections: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL (by UV absorbance at 280 nm)
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缓冲液
- 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide, None
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at-20 °C.
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- JAG1 (Jagged 1 (JAG1))
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别名
- CD339 / JAG1
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背景
- Jagged 1 protein encoded by the JAG1 gene, that is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the Jagged 1 protein cause Alagille syndrome. Jagged 1 signaling through notch 1 has also been shown to play a role in hematopoies.Synonyms: JAGL1, Jagged-1, hJ1
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基因ID
- 182
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NCBI登录号
- NP_000205
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UniProt
- P78504
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途径
- Notch Signaling, Stem Cell Maintenance
抗原
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