SARM1 抗体
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北京 101111
Quick Overview for SARM1 抗体 (ABIN400726)
抗原
See all SARM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes Sterile Alpha And TIR Motif Containing 1 (SARM1).
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交叉反应 (详细)
- Species reactivity (tested):Human.
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产品特性
- Synonyms: SARM, SAMD2, KIAA0524, Sterile alpha and TIR motif-containing protein 1, SAMdomain-containing protein 2, Sterile alpha and Armadillo repeat protein, Sterile alphamotif domain-containing protein 2
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纯化方法
- Protein G Chromatography.
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免疫原
- Synthetic peptide - KLH conjugated.
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亚型
- IgG2b
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应用备注
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Immunoprecipitation: 1/200. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 10 % Glycerol and 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))
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别名
- SARM1
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背景
- Toll-like receptors (TLRs) play an essential role in the detection and elimination of invading microbes. They are type-1 transmembrane receptors, containing extracellular leucine rich repeats and an intracellular Toll/interleukin-1 receptor (TIR) domain. Upon stimulation, these receptors interact with specific TIR domain-containing adaptor proteins. Five such adaptors have been discovered to date, MyD88, Mal (MyD88 adaptor-like)/TIRAP (TIR domain-containing adaptor protein), Trif (TIR-domain-containing adaptor inducing interferon-beta), TRAM (Trif-related adaptor molecule) and SARM (SAM and ARM-containing protein). Different TLRs use different combinations of these adaptors, leading to the activation of common and unique pathways involved in the elimination of the invading microbe.Synonyms: KIAA0524, SAM domain-containing protein 2, SAMD2, SARM, Sterile alpha and Armadillo repeat protein, Sterile alpha and TIR motif-containing protein 1, Sterile alpha motif domain-containing protein 2
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基因ID
- 23098
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UniProt
- Q6SZW1
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途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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