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SARM1 抗体

This anti-SARM1 antibody is a 小鼠 单克隆 antibody detecting SARM1 in IHC (p) 和 IP. Suitable for 人.
产品编号 ABIN400726
发货至: 中国

Quick Overview for SARM1 抗体 (ABIN400726)

抗原

See all SARM1 抗体
SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SARM1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

克隆位点

Sarmy-1
  • 特异性

    This antibody recognizes Sterile Alpha And TIR Motif Containing 1 (SARM1).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    产品特性

    Synonyms: SARM, SAMD2, KIAA0524, Sterile alpha and TIR motif-containing protein 1, SAMdomain-containing protein 2, Sterile alpha and Armadillo repeat protein, Sterile alphamotif domain-containing protein 2

    纯化方法

    Protein G Chromatography.

    免疫原

    Synthetic peptide - KLH conjugated.

    亚型

    IgG2b
  • 应用备注

    Immunoprecipitation: 1/200. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 10 % Glycerol and 0.02 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

    别名

    SARM1

    背景

    Toll-like receptors (TLRs) play an essential role in the detection and elimination of invading microbes. They are type-1 transmembrane receptors, containing extracellular leucine rich repeats and an intracellular Toll/interleukin-1 receptor (TIR) domain. Upon stimulation, these receptors interact with specific TIR domain-containing adaptor proteins. Five such adaptors have been discovered to date, MyD88, Mal (MyD88 adaptor-like)/TIRAP (TIR domain-containing adaptor protein), Trif (TIR-domain-containing adaptor inducing interferon-beta), TRAM (Trif-related adaptor molecule) and SARM (SAM and ARM-containing protein). Different TLRs use different combinations of these adaptors, leading to the activation of common and unique pathways involved in the elimination of the invading microbe.Synonyms: KIAA0524, SAM domain-containing protein 2, SAMD2, SARM, Sterile alpha and Armadillo repeat protein, Sterile alpha and TIR motif-containing protein 1, Sterile alpha motif domain-containing protein 2

    基因ID

    23098

    UniProt

    Q6SZW1

    途径

    TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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