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ULK2 抗体 (N-Term)

This anti-ULK2 antibody is a 兔 多克隆 antibody detecting ULK2 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN392692
发货至: 中国

Quick Overview for ULK2 抗体 (N-Term) (ABIN392692)

抗原

See all ULK2 抗体
ULK2 (Unc-51 Like Kinase 2 (ULK2))

适用

  • 51
  • 16
  • 7

宿主

  • 41
  • 10

克隆类型

  • 42
  • 9
多克隆

标记

  • 32
  • 5
  • 4
  • 4
  • 3
  • 3
This ULK2 antibody is un-conjugated

应用范围

  • 40
  • 34
  • 15
  • 7
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB12561
  • 抗原表位

    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 235-264, N-Term

    预测反应

    M

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This ULK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-264 amino acids from the N-terminal region of human ULK2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    ULK2 (Unc-51 Like Kinase 2 (ULK2))

    别名

    ULK2

    背景

    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Two human homologs of the yeast autophagy-specific kinase exist: ULK1(APG1) and ULK2. APG1 plays a critical role in regulating key elements of the autophagy pathway. APG1 stimulates autophagy, leading to autophagy-dependent restriction of cell growth and ultimately cell apoptosis at high levels of activity, and is a negative regulator of mTOR signaling.

    分子量

    112694

    基因ID

    9706

    NCBI登录号

    NP_001136082, NP_055498

    UniProt

    Q8IYT8

    途径

    Regulation of Cell Size, Autophagy
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