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PAK4 抗体 (N-Term)

This anti-PAK4 antibody is a 兔 多克隆 antibody detecting PAK4 in WB 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN392437
发货至: 中国

Quick Overview for PAK4 抗体 (N-Term) (ABIN392437)

抗原

See all PAK4 抗体
PAK4 (P21-Activated Kinase 4 (PAK4))

适用

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  • 42
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  • 5
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人, 小鼠

宿主

  • 68
  • 6
  • 1

克隆类型

  • 67
  • 8
多克隆

标记

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This PAK4 antibody is un-conjugated

应用范围

  • 59
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  • 1
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  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB01233
  • 抗原表位

    • 15
    • 9
    • 7
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    AA 156-187, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This PAK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-187 amino acids from the N-terminal region of human PAK4.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    PAK4 (P21-Activated Kinase 4 (PAK4))

    别名

    PAK4

    背景

    PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.

    分子量

    64072

    基因ID

    10298

    NCBI登录号

    NP_001014831, NP_001014832, NP_001014834, NP_001014835, NP_005875

    UniProt

    O96013

    途径

    RTK signaling
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