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alpha Actinin 4 抗体 (N-Term)

This anti-alpha Actinin 4 antibody is a 兔 多克隆 antibody detecting alpha Actinin 4 in WB. Suitable for 人.
产品编号 ABIN392218
发货至: 中国

Quick Overview for alpha Actinin 4 抗体 (N-Term) (ABIN392218)

抗原

See all alpha Actinin 4 (ACTN4) 抗体
alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

适用

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宿主

  • 93
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克隆类型

  • 78
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多克隆

标记

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This alpha Actinin 4 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB15650
  • 抗原表位

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    AA 192-220, N-Term

    预测反应

    B, C, M, Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This ACTN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-220 amino acids from the N-terminal region of human ACTN4.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

    别名

    ACTN4

    背景

    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This protein is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and is thought to be involved in metastatic processes. Mutations in the gene encoding this protein have been associated with focal and segmental glomerulosclerosis.

    分子量

    104854

    基因ID

    81

    NCBI登录号

    NP_004915

    UniProt

    O43707

    途径

    Proton Transport
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