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RYK 抗体 (C-Term)

Cited in 2+ publications. This anti-RYK antibody is a 兔 多克隆 antibody detecting RYK in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN392051
发货至: 中国
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Quick Overview for RYK 抗体 (C-Term) (ABIN392051)

抗原

See all RYK 抗体
RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

适用

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宿主

  • 54
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克隆类型

  • 49
  • 23
多克隆

标记

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This RYK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB1494
  • 抗原表位

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    AA 561-591, C-Term

    预测反应

    M

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This RYK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 561-591 amino acids from the C-terminal region of human RYK.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Santiago, Oguma, Brown, Laurence: "Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir." in: Biochemical and biophysical research communications, Vol. 417, Issue 1, pp. 223-30, (2012) (PubMed).

    Keeble, Halford, Seaman, Kee, Macheda, Anderson, Stacker, Cooper: "The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 21, pp. 5840-8, (2006) (PubMed).

  • 抗原

    RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

    别名

    RYK

    背景

    RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.

    分子量

    67815

    基因ID

    6259

    NCBI登录号

    NP_001005861, NP_002949

    UniProt

    P34925

    途径

    RTK signaling, WNT signaling, Regulation of Cell Size
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