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RYK 抗体 (AA 160-190)

Name: RYK 抗体 (AA 160-190)
SKU: ABIN392050
Availability: OutOfStock

Cited in 4+ publications. This 兔多克隆 anti-RYK antibody (Clone RB1491) specifically detects RYK in WB 和 IHC (p). The antibody is reactive with 人, 小鼠和大鼠 samples.

Western blot analysis of lysate from mouse NIH/3T3 cell line, using RYK Antibody (ABIN392050 and ABIN2841818). (RYK 抗体 (AA 160-190))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (RYK 抗体 (AA 160-190))

IHC (p)

Western blot analysis of lysate from human ovary tissue lysate, using RYK Antibody (ABIN392050 and ABIN2841818). (RYK 抗体 (AA 160-190))

Western blot analysis of lysates from mouse lung and ovary tissue lysate(from left to right), using RYK Antibody (ABIN392050 and ABIN2841818). (RYK 抗体 (AA 160-190))

The anti-RYK Pab (ABIN392050 and ABIN2841818) is used in Western blot to detect RYK in Jurkat cell lysate. (RYK 抗体 (AA 160-190))

Western blot analysis of RYK (arrow) using rabbit polyclonal RYK Antibody (ABIN392050 and ABIN2841818). (RYK 抗体 (AA 160-190))

7 images

(4 references)

产品编号 ABIN392050

发货至: 中国

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中国
北京 101111

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Quick Overview for RYK 抗体 (AA 160-190) (ABIN392050)

抗原

See all RYK 抗体

RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This RYK antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB1491

抗原表位
8

7

7

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 160-190

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This RYK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-190 amino acids from human RYK.

亚型

Ig Fraction
anti-RYK Receptor-Like Tyrosine Kinase (RYK) (AA 494-586) antibody
RYK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-RYK Receptor-Like Tyrosine Kinase (RYK) (AA 287-533) antibody
RYK 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-RYK Receptor-Like Tyrosine Kinase (RYK) antibody
RYK 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5080 unconjugated Recombinant Antibody

anti-RYK Receptor-Like Tyrosine Kinase (RYK) (AA 260-565) antibody
RYK 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1671CT575-42-61 unconjugated

anti-RYK Receptor-Like Tyrosine Kinase (RYK) (AA 308-570) antibody
RYK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-RYK Receptor-Like Tyrosine Kinase (RYK) (AA 561-591), (C-Term) antibody
RYK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1494 unconjugated

anti-RYK Receptor-Like Tyrosine Kinase (RYK) antibody
RYK 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1C1 unconjugated

anti-RYK Receptor-Like Tyrosine Kinase (RYK) (AA 1-610) antibody
RYK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-RYK Receptor-Like Tyrosine Kinase (RYK) (AA 150-200) antibody
RYK 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-RYK Receptor-Like Tyrosine Kinase (RYK) (C-Term) antibody
RYK 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze-thaw cycles.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

有效期

6 months
Povinelli, Nemeth: "Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor." in: Stem cells (Dayton, Ohio), Vol. 32, Issue 1, pp. 105-15, (2014) (PubMed).

González, Fernández-Martos, Arenas, Rodríguez: "The Ryk receptor is expressed in glial and fibronectin-expressing cells after spinal cord injury." in: Journal of neurotrauma, Vol. 30, Issue 10, pp. 806-17, (2013) (PubMed).

Santiago, Oguma, Brown, Laurence: "Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir." in: Biochemical and biophysical research communications, Vol. 417, Issue 1, pp. 223-30, (2012) (PubMed).

Miyashita, Koda, Kitajo, Yamazaki, Takahashi, Kikuchi, Yamashita: "Wnt-Ryk signaling mediates axon growth inhibition and limits functional recovery after spinal cord injury." in: Journal of neurotrauma, Vol. 26, Issue 7, pp. 955-64, (2009) (PubMed).
抗原

RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

别名

RYK

背景

RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.

分子量

67815

基因ID

6259

NCBI登录号

NP_001005861, NP_002949

UniProt

P34925

途径

RTK signaling, WNT signaling, Regulation of Cell Size