ROR2 抗体
(2 references)Quick Overview for ROR2 抗体 (ABIN392046)
抗原
See all ROR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This ROR2 antibody is generated from rabbits immunized with a recombinant protein of human ROR2.
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亚型
- Ig Fraction
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anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 683-934) antibody
ROR2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 59-155) antibodyROR2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6F2D10 unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 19-50), (N-Term) antibodyROR2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB01507-01508 unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 19-50) antibodyROR2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 752-926) antibodyROR2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 915-943), (C-Term) antibodyROR2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01510 unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (Internal Region) antibodyROR2 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 34-143) antibodyROR2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E1 unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) antibodyROR2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ROR2-1911 unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 100-200) antibodyROR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Association between Wnt inhibitory factor 1 and receptor tyrosine kinase-like orphan receptor 2 protein expression and the clinical pathological significance in benign and malignant pancreatic ..." in: Oncology letters, Vol. 13, Issue 4, pp. 2244-2252, (2017) (PubMed).
: "RoR2 functions as a noncanonical Wnt receptor that regulates NMDAR-mediated synaptic transmission." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 15, pp. 4797-802, (2015) (PubMed).
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: "Association between Wnt inhibitory factor 1 and receptor tyrosine kinase-like orphan receptor 2 protein expression and the clinical pathological significance in benign and malignant pancreatic ..." in: Oncology letters, Vol. 13, Issue 4, pp. 2244-2252, (2017) (PubMed).
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- ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))
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别名
- ROR2
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背景
- ROR2 is a tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. This Type I membrane protein is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Defects in ROR2 are a cause of brachydactyly type B1 (BDB1). BDB1 is an autosomal dominant skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In BDB1 the middle phalanges are short but in addition the terminal phalanges are rudimentary or absent. Both fingers and toes are affected. The thumbs and big toes are usually deformed. Defects in ROR2 are a cause of recessive Robinow syndrome (RRS). RRS is an autosomal disorder characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly and a dysmorphic facial appearance. The protein contains 1 frizzled (FZ) domain, 1 immunoglobulin-like C2-type domain, and 1 kringle domain.
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分子量
- 104757
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基因ID
- 4920
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NCBI登录号
- NP_004551
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UniProt
- Q01974
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途径
- RTK signaling, WNT signaling
抗原
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