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MUSK 抗体
This anti-MUSK antibody is a 兔 多克隆 antibody detecting MUSK in WB, FACS 和 IF. Suitable for 人 和 小鼠.
Quick Overview for MUSK 抗体 (ABIN392021)
抗原
See all MUSK 抗体
MUSK
(Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
适用
All reactivities for MUSK 抗体
人, 小鼠
宿主
All hosts for MUSK 抗体
兔
克隆类型
All clonalities for MUSK 抗体
多克隆
标记
All conjugates for MUSK 抗体
This MUSK antibody is un-conjugated
应用范围
All applications for MUSK 抗体
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
克隆位点
RB14743
MUSK抗体详情
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纯化方法
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
免疫原
This MUSK antibody is generated from rabbits immunized with human MUSK recombinant protein.
亚型
Ig Fraction
Alternatives
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使用细节
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应用备注
IF: 1:10~50. WB: 1:1000. FC: 1:10~50
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期
6 months
MUSK目标详情
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抗原
MUSK
(Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
别名
MUSK
背景
MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
分子量
97056
基因ID
4593
NCBI登录号
NP_001159752 , NP_001159753 , NP_005583
UniProt
O15146
途径
RTK signaling , Regulation of Muscle Cell Differentiation , Synaptic Membrane , Regulation of Cell Size , Skeletal Muscle Fiber Development
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