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            MUSK 抗体 
                                    This anti-MUSK antibody is a 兔 多克隆 antibody detecting MUSK in WB, FACS 和 IF. Suitable for 人 和 小鼠.
            
                            
                        
         
        
                
            
    Quick Overview for MUSK 抗体 (ABIN392021) 
                        
                抗原
             
                                                See all MUSK 抗体 
                                        
                MUSK
                                    (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
                            
                                    
                适用
             
                            
                                
                                    All reactivities for MUSK 抗体
                                     
                 
                
                        
                人, 小鼠
            
                                    
                宿主
             
                            
                                
                                    All hosts for MUSK 抗体
                                     
                 
                
                        
                兔
            
                                    
                克隆类型
             
                            
                                
                                    All clonalities for MUSK 抗体
                                     
                 
                
                        
                多克隆
            
                                    
                标记
             
                            
                                
                                    All conjugates for MUSK 抗体
                                     
                 
                
                        
                This MUSK antibody is un-conjugated
            
                                    
                应用范围
             
                            
                                
                                    All applications for MUSK 抗体
                                     
                 
                
                        
                Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
            
                                            
                克隆位点
             
                        
                RB14743
            
                                        
                         
                
    
        
            MUSK抗体详情 
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                                            纯化方法 
                                             
                                                    
                        This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
                                             
                                                                                                                                
                                            免疫原 
                                             
                                                    
                        This MUSK antibody is generated from rabbits immunized with human MUSK recombinant protein.
                                             
                                                                                                                                                            
                                            亚型 
                                             
                                                    
                        Ig Fraction
                                             
                                                                     
 
                                
    
        
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            使用细节 
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                                            应用备注 
                                             
                                                    
                        IF: 1:10~50. WB: 1:1000. FC: 1:10~50
                                             
                                                                                                                                
                                            限制 
                                             
                                                    
                        仅限研究用
                                             
                                         
 
                
                
    
        
            贮存及处理 
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                                            状态 
                                             
                                                    
                        Liquid
                                             
                                                                                                                                
                                            缓冲液 
                                             
                                                    
                        Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
                                             
                                                                                                                                
                                            储存液 
                                             
                                                    
                        Sodium azide
                                             
                                                                                                                                
                                            注意事项 
                                             
                                                    
                        This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
                                             
                                                                                                                                
                                            储存条件 
                                             
                                                    
                        4 °C,-20 °C
                                             
                                                                                                                                
                                            储存方法 
                                             
                                                    
                        Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
                                             
                                                                                                                                
                                            有效期 
                                             
                                                    
                        6 months
                                             
                                         
 
                
                
    
        
            MUSK目标详情 
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                        抗原
                                             
                                                    
                        MUSK
                                                    (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
                                             
                                                                                                                                
                                            别名 
                                             
                                                    
                        MUSK
                                             
                                                                                                                                
                                            背景 
                                             
                                                    
                        MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
                                             
                                                                                                                                
                                            分子量 
                                             
                                                    
                        97056
                                             
                                                                                                                                
                                            基因ID 
                                             
                                                    
                        4593
                                             
                                                                                                                                
                                            NCBI登录号 
                                             
                                                    
                        NP_001159752 , NP_001159753 , NP_005583 
                                             
                                                                                                                                
                                            UniProt 
                                             
                                                    
                        O15146 
                                             
                                                                                                                                
                                            途径 
                                             
                                                    
                        RTK signaling , Regulation of Muscle Cell Differentiation , Synaptic Membrane , Regulation of Cell Size , Skeletal Muscle Fiber Development 
                                             
                                         
 
                                
                    
                        
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