EPH Receptor B6 抗体 (C-Term)
(3 references)Quick Overview for EPH Receptor B6 抗体 (C-Term) (ABIN391928)
抗原
See all EPH Receptor B6 (EPHB6) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 990-1021, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This EphB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 990-1021 amino acids from the C-terminal region of human EphB6.
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亚型
- Ig Fraction
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anti-EPH Receptor B6 (EPHB6) (AA 23-122) antibody
EPHB6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5D8 unconjugated
anti-EPH Receptor B6 (EPHB6) (Internal Region) antibodyVerified EPHB6 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-EPH Receptor B6 (EPHB6) (AA 410-553) antibodyEPHB6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B6 (EPHB6) (Internal Region) antibodyEPHB6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B6 (EPHB6) (AA 601-750) antibodyEPHB6 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 2A6B9 unconjugated
anti-EPH Receptor B6 (EPHB6) antibodyEPHB6 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 8E7H12 unconjugated
anti-EPH Receptor B6 (EPHB6) (AA 551-650) antibodyEPHB6 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B6 (EPHB6) antibodyEPHB6 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B6 (EPHB6) (AA 23-122) antibodyEPHB6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5D8 unconjugated
anti-EPH Receptor B6 (EPHB6) (AA 45-74), (N-Term) antibodyEPHB6 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB1663 unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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: "Expression of EphB6 in ovarian serous carcinoma is associated with grade, TNM stage and survival." in: Journal of clinical pathology, (2015) (PubMed).
: "Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome." in: PLoS ONE, Vol. 6, Issue 9, pp. e24426, (2011) (PubMed).
: "The EPHB6 receptor tyrosine kinase is a metastasis suppressor that is frequently silenced by promoter DNA hypermethylation in non-small cell lung cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 8, pp. 2275-83, (2010) (PubMed).
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: "Expression of EphB6 in ovarian serous carcinoma is associated with grade, TNM stage and survival." in: Journal of clinical pathology, (2015) (PubMed).
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- EPH Receptor B6 (EPHB6)
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别名
- EphB6
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背景
- Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB6 lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
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分子量
- 110700
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基因ID
- 2051
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NCBI登录号
- NP_001267723, NP_001267724, NP_004436
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UniProt
- O15197
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途径
- RTK signaling, Hormone Transport
抗原
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